نتایج جستجو برای: double perfused model

تعداد نتایج: 2328463  

Ali Reza Arshadi Khamseh Majid Aminnayyeri Seyyed Mohammad Taghi Fatemi Ghomi

The paper presents an economical model for double variable acceptance sampling with inspection errors. Taguchi cost function is used as acceptance cost while quality specification functions are normal with known variance. An optimization model is developed for double variables acceptance sampling scheme at the presence of inspection errors with either constant or monotone value functions. The m...

2009
Hilary Kathleen Siddall Hilary Siddall Mihaela Mocanu Derek Hausenloy

Activation of the PI3K/AKT pathway protects the heart from ischaemia-reperfusion injury. Phosphatase and Tensin Homolog deleted on Chromosome10 (PTEN) is a negative regulator of this pathway. The hypothesis on which this thesis was based stated that inhibition of PTEN would confer protection against ischaemia-reperfusion injury. PTEN was reduced using: 1) a PTEN inhibitor, bpV(HOpic), 2) a mous...

Journal: :Cancer research 1983
P L Skipper J F Tomera J S Wishnok H Brunengraber S R Tannenbaum

A pharmacokinetic model was constructed to describe the absorption, distribution, and metabolic clearance of N-nitrosodimethylamine. The model is composed of two compartments, total body water and the liver, which are linked by blood flow. Metabolic clearance is presumed to occur only in the liver. Liver clearance kinetics was determined with isolated perfused livers. Clearance appeared to obey...

Journal: :The British journal of nutrition 2006
Sophie Lafay Christine Morand Claudine Manach Catherine Besson Augustin Scalbert

The absorption and metabolism in the small intestine of chlorogenic acid (5-O-caffeoylquinic acid), the main phenolic acid in the human diet, and of caffeic acid were studied in rats in order to determine whether chlorogenic acid is directly absorbed or hydrolysed in the small intestine. Chlorogenic and caffeic acids were perfused into a segment of ileum plus jejunum during 45 min (50 microm, 0...

2015
Gert Jan Pelgrim Marco Das Ulrike Haberland Cees Slump Astri Handayani Sjoerd van Tuijl Marco Stijnen Ernst Klotz Matthijs Oudkerk Joachim E. Wildberger Rozemarijn Vliegenthart

OBJECTIVE To test the feasibility of a CT-compatible, ex vivo, perfused porcine heart model for myocardial perfusion CT imaging. METHODS One porcine heart was perfused according to Langendorff. Dynamic perfusion scanning was performed with a second-generation dual source CT scanner. Circulatory parameters like blood flow, aortic pressure, and heart rate were monitored throughout the experimen...

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