The effect of pH on the pain of administration and efficacy of 1% lignocaine was investigated in a prospective, double-blind, randomized study of 20 adult volunteers. Onset and spread of anaesthesia by intra-dermal injection were not altered, but there was a significant reduction in pain scores with a higher pH. Overall, pain scores appear to be more dependent on the speed of injection rather t...

Capsule application of Diamidino Yellow (DY) to the cut end of the sciatic nerve immediately followed by capsule application of Fast Blue (FB) resulted in approximately 95% double-labelled dorsal root ganglion neurones (DRGn) and motoneurones (Mn). Nerve injection of DY followed either immediately or 2 months later by capsule application of FB resulted in approximately 90% double-labelled DRGn ...

A particle injection model has been applied to the radio outbursts of the X-ray binary Circinus X-1. The radio outbursts of this system have often been observed to exhibit a double peaked structure, i.e., with two apparent consecutive maxima. We show here that particle injection models can account for such observed behaviour provided that a time variable particle injection rate is adopted. Seve...

Adrenalectomized rats are 1000 times more sensitive to lethal effects of the double-stranded complex polyriboinosinic.polyribocytidylic acid than intact rats. They are protected from such lethal effects by corticosterone. The complex can rapidly induce diffuse, severe necrosis of villous epithelium in small intestine without damage in crypts. Injection of the individual homopolymers, polyriboin...

purpose: to evaluate the effects of posterior subtenon triamcinolone acetonide (ta) injection on clinical, angiographic, and optical coherence tomographic (oct) features in refractory diabetic macular edema (dme). method: in a randomized double-masked placebo-controlled clinical trial, 38 consecutive patients (64 eyes) with dme refractory to previous laser therapy or not suitable for such treat...

A prospective, randomised, double-blind study of 28 patients presenting with Achilles paratendonitis was undertaken in order to evaluate the role of peritendonous injection of methy prednisolone acetate (Depo Medrone). At presentation patients were either administered peri-tendonous injection of 40 mgs of methyl prednisolone acetate suspended in 1 ml of 0.25% marcaine or 2 ml of 0.25% marcaine ...

Article history: Received 25 October 2016 Received in revised form 15 January 2017 Accepted 26 January 2017 Available online 30 January 2017 transmission method in Puerto Rico is injection drug use—42% of male HIV cases are attributed to injection drug use, exactly double that of the U.S. as a whole which attributes 21% of male HIV cases to injection drug use. HCV has a prevalence among the gen...

Excruciating pain is a common complication following breast surgery which can be effectively treated with double path PECS I and II blocks. Sixty patients undergoing were randomly assigned into two groups: Single-path (SP) group received single-path pectoral nerve (PECS) block, by injecting 0.25% bupivacaine 15 ml the space between serratus muscle pectoralis minor muscle, then withdrawing needl...

BACKGROUND This randomized, double-blind, multi-center, non-inferiority trial was conducted to assess the efficacy and safety of a cross-linked hyaluronate (XLHA, single injection form) compared with a linear high molecular hyaluronate (HMWHA, thrice injection form) in patients with symptomatic knee osteoarthritis. METHODS Two hundred eighty seven patients with osteoarthritis (Kellgren-Lawren...