An efficient strategy for selective fluorescent detection of Cu(2+) was developed based on the carbon quantum dots (CQDs) nanoconjugated with a specific organic molecule, amino TPEA, and further applied to intracellular sensing and imaging of Cu(2+) as a consequence of the fluorescence properties and the established low cytotoxicity of CQDs.

Biomolecule-mimicking nitrogen-doped carbon dots (N-Cdots) were synthesized from dopamine by a neutralization heat strategy. Fluorescence imaging of various cells validated their nucleus-staining efficiency. The dopamine-mimicking N-Cdots "trick" nuclear membranes to achieve nuclear localization and imaging.

A universal and label-free photoelectrochemical cytosensing strategy was designed based on resonance energy transfer (RET) between carbon dots and cysteamine capped gold nanoparticles. RET promoted photo-to-current conversion efficiency and enhanced detection sensitivity. This proposed photoelectrochemical cytosensing platform exhibited a good performance for the assay of tumor cells with overe...

A new strategy toward controllable release of NO for therapeutic purpose is described. Mn(2+)-doped ZnS quantum dots with NIR-II to visible upconversion properties were encapsulated by chitosan, with which photochemical NO precursors were conjugated to generate nanostructured materials capable of releasing NO under NIR-II irradiation.

Irradiation of CdSe-ZnS quantum dots (QDs) with visible light in the presence of [PtCl(4)(bpy)] (1) (bpy = 2,2'-bipyridine) produced with high efficiency [PtCl(2)(bpy)] (2) by photoinduced electron transfer; a reaction and strategy which opens up new opportunities for cancer therapy.

A novel electrochemiluminescent (ECL) cytosensing strategy for sensitive dynamic monitoring of carbohydrate expression on living cells was designed by combining the specific recognition of lectin to carbohydrate groups with the functionalization of immobilized CdSe quantum dots, which acted as ECL emitting species.

A simple strategy for the fabrication of the first biosensor based on the intrinsic electrochemiluminescence of quantum dots coupled with an enzymatic reaction is proposed with glucose oxidase as a model, which could be applied in more bioanalytical systems for oxidase substrates.

TB control programs currently emphasize the Direct Observed Therapy Short-Course (DOTS) strategy, promoted by the World Health Organization and the International UNION Against Tuberculosis and Lung Disease. The current goals are to achieve 85% treatment success and 70% case detection. Among others, TB global control currently confronts two challenges to meet those goals: diagnosis delay and non...

We study misère Dots-and-Boxes, where the goal is to minimize score, for narrow boards. In particular, we characterize the winner for 1× n boards with an explicit winning strategy for the first player with a score of b(n − 1)/3c. We also give preliminary results for 2 × n and for Swedish 1× n (where the boundary is initially drawn).