Background:The most efficient application of ionizing radiation is serving medical purposes and using this radiation has caused people to learn that artificial sources of radiation exposure among these resources can be of highest exposure rate.  Objective: The present study is aimed at initially establishing a baseline for local-reference dose level in Mazandaran, Iran in 12 projections of the...

The aim of this study was to compare IMRT optimization in the CMS XiO radiotherapy treatment planning system, with and without segment weight optimization. Twenty-one prostate cancer patients were selected for this study. All patients were initially planned with step-and-shoot IMRT (S-IMRT). A new plan was then created for each patient by applying the segment weight optimization tool (SWO-IMRT)...

PURPOSE Traditionally, the tongue-and-groove effect due to the multileaf collimator architecture in intensity-modulated radiation therapy (IMRT) has typically been deferred to the leaf sequencing stage. The authors propose a new direct aperture optimization method for IMRT treatment planning that explicitly incorporates dose calculation inaccuracies due to the tongue-and-groove effect into the ...

PURPOSE Inverse planning is trial-and-error iterative process. This work introduces a fully automated inverse optimization approach, where the treatment plan is closely tailored to the unique patient anatomy. The auto-optimization is applied to pancreatic stereotactic body radiotherapy (SBRT). MATERIALS AND METHODS The automation is based on stepwise reduction of dose-volume histograms (DVHs)...

Inverse optimization of robotic stereotactic lung radiotherapy is typically performed using relatively simple dose calculation algorithm on a single instance of breathing geometry. Variations of patient geometry and tissue density during respiration could reduce the dose accuracy of these 3D optimized plans. To quantify the potential benefits of direct four-dimensional (4D) optimization in robo...

although many methods exist for intensity modulated radiotherapy (imrt) fluence map optimization for crisp data, based on clinical practice, some of the involved parameters are fuzzy. in this paper, the best fluence maps for an imrt procedure were identifed as a solution of an optimization problem with a quadratic objective function, where the prescribed target dose vector was fuzzy. first, a d...

We apply the NSGA-II algorithm and its controlled elitist version NSGA-IIc for the intensity modulated beam radiotherapy dose optimization problem. We compare the performance of the algorithms with objectives for which deterministic optimization methods provide global optimal solutions. The number of parameters to be optimized can be up to a few thousands and the number of objectives varies fro...

The aim of this work is to develop and investigate an inverse treatment planning process (TPP) for mixed beam radiotherapy (MBRT) capable of performing simultaneous optimization of photon and electron apertures. A simulated annealing based direct aperture optimization (DAO) is implemented to perform simultaneous optimization of photon and electron apertures, both shaped with the photon multilea...