Mycotoxins can reduce fertility and development in livestock, notably in pigs and poultry, although the effect of most mycotoxins on reproductive function in cattle has not been established. One major mycotoxin, deoxynivalenol (DON), not only targets immune cells and activates the ribotoxic stress response (RSR) involving MAPK activation, but also inhibits oocyte maturation in pigs. In this stu...

Deoxynivalenol (DON) is a mycotoxin affecting wheat quality. The formation of the "masked" mycotoxin deoxinyvalenol-3-glucoside (D3G) results from a defense mechanism the plant uses for detoxification. Both mycotoxins are important from a food safety point of view. The aim of this work was to analyze DON and D3G content in inoculated near-isogenic wheat lines grown at two locations in Minnesota...

Both mycotoxin contamination of feed and Clostridium perfringens-induced necrotic enteritis have an increasing global economic impact on poultry production. Especially the Fusarium mycotoxin deoxynivalenol (DON) is a common feed contaminant. This study aimed at examining the predisposing effect of DON on the development of necrotic enteritis in broiler chickens. An experimental Clostridium perf...

dissolved organic nitrogen (don) is an important constituent of dissolved organic matter (dom). it has a considerable effect on total dissolved soil nitrogen and it is very important as a nitrogen source of many aquatic and terrestrial ecosystems. dissolved inorganic nitrogen, which is another form of total soil dissolved nitrogen, includes no3, no2 and nh4, which is very important for plant nu...

O objetivo foi avaliar a capacidade das espécies fúngicas Aspergillus oryzae e Rhizopus oryzae em degradar desoxinivalenol (DON) em fermentação submersa. O meio submerso utilizado foi água destilada estéril contaminada com 1mg mL DON, inoculado com 4 × 10 esporos mL das espécies fúngicas. A amostragem foi realizada a cada 48 h até 240 h de processo, determinando a massa residual de DON, percent...

Physiological regulations of energy balance and body weight imply highly adaptive mechanisms which match caloric intake to caloric expenditure. In the central nervous system, the regulation of appetite relies on complex neurocircuitry which disturbance may alter energy balance and result in anorexia or obesity. Deoxynivalenol (DON), a trichothecene, is one of the most abundant mycotoxins found ...

On the basis of mass balance calculations performed for nitrogen (N) uptake experiments in the Southern California Bight (SCB), it has been suggested that a significant portion of dissolved inorganic N (DIN) uptake results in the production of dissolved organic N (DON). To investigate this process, the fate of ammonium (NH4 ) and nitrate (NO3 ) uptake was quantified within the euphotic zone at ...

'The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects. Through consumption of contaminated cereals and cereal products, human and pigs are exposed to this mycotoxin. Using in vitro, ex vivo and in vivo appro...

BACKGROUND AND AIMS Both deoxynivalenol (DON) and nontyphoidal salmonellosis are emerging threats with possible hazardous effects on both human and animal health. The objective of this study was to examine whether DON at low but relevant concentrations interacts with the intestinal inflammation induced by Salmonella Typhimurium. METHODOLOGY By using a porcine intestinal ileal loop model, we i...