Introduction: Oocyte quality and fertility decline with advanced maternal age. During maturation within the ovarian follicle, oocyte relies on associated somatic cells, specifically cumulus granulosa to acquire essential components for developmental capacity. Methods: A nontargeted metabolomics approach was used investigate effects of mare age different cell types dominant, follicular-phase fol...

Trichoepithelioma is an uncommon, benign hamartomatous tumor of the pilosebaceous follicle. Presenting as multiple papules and nodules on face and neck, they pose a significant cosmetic problem in affected individuals. Familial involvement of this dermatosis occurs in an autosomal dominant pattern, the locus being located on chromosome 9p21, which causes multiple facial lesions in family member...