Abstract Background We aimed to develop and validate a predictive model for the overall survival (OS) of patients with nasopharyngeal carcinoma (NPC). Methods Overall, 519 were retrospectively reviewed in this study. In addition, random forest was used identify significant prognostic factors OS among NPC patients. Then, calibration plot concordance index (C-index) utilized evaluate accuracy nom...

The intron-exon structure of Khorasan native fowl interleukin-2 (IL-2) was investigated. For this purpose, twenty chickens were selected from the Native Fowl Breeding Station of Khorasan province, and genomic DNA was extracted using a modified conventional DNA extraction protocol. An 875 bp fragment of IL-2 was successfully amplified, including a small part of the promoter, exon 1, intron 1, an...

identification of host blood meal in haematophagous arthropods is an important element in their rule in transmission of vector borne diseases. the effects of post ingestion and physical conditions that killed mosquitoes are stored on the success of detecting blood meal dna of anopheles stephensi and culex quinquefasiatus was investigated by polymerase chain reaction (pcr) amplification at the h...

introduction: silymarin is obtained from silybum marianum (milk thistle), an edible plant that has long been used medicinally for the treatment of liver-related disorders. silymarin is a powerful hepatoprotective and antioxidant but the anticlastogenic activity, which is an important aspect of its cancer chemoprevention is not known hence the present investigation was carried out to study its a...

background clinical observations have shown that patients infected with chronic hepatitis b virus (hbv) genotype c versus genotype b had a higher load of the virus, more serious illness, and poorer responses to antiviral therapy and prognosis. however, the disparity between the two has not been clarified. objectives to explore possible relationship between hbv genotypes b and c and peripheral b...

In this study at first , an azo dye, 2,7- naphthalenediol, 2-[(4-Bromophenyl)azo (BPAND) as a ligand has been synthesized by addition of p-Bromoaniline to the modified montomorillonite K10 clay. This ligand was characterized using 1H-NMR, UV-Vis and IR spectroscopies. Subsequently, its interaction with calf thymus deoxyribonucleicacid ,ct-DNA was investigated in 5 mM phosphate buffer solution, ...