BACKGROUND Data on comparative healthcare resource utilization and costs associated with the newer oral disease-modifying therapies (DMTs) for managing relapsing-remitting multiple sclerosis (MS) in routine clinical practice are limited. The purpose of this study was to estimate healthcare resource utilization, costs, and relapse rates in the year after initiating treatment with dimethyl fumara...

BACKGROUND Glatiramer acetate (GA) and interferon-beta (IFN-β) are disease-modifying therapies (DMTs) for multiple sclerosis that are administered through subcutaneous (SC) or intramuscular (IM) injections. Skin reactions associated with DMTs are common and may influence patient's health-related quality of life (QoL). We aimed to determine the prevalence of cutaneous adverse events associated w...

BACKGROUND AND PURPOSE When to start disease-modifying treatment (DMT) in patients with a clinically isolated syndrome (CIS) requires individual weighing of benefits versus possible burden of side effects and costs. How this occurs in a routine setting is barely known. The aim of the study was to investigate the decision-making process regarding immediate or later DMT and the ensuing impact on ...

This intervention study examined the correlation between specific DMT interventions and the improvement in quality of life, stress management, and stress reduction. Dance therapists (N=11) completed 970 Intervention Checklist 1 (specific interventions at the individual level) and 120 Intervention Checklist 2 (specific interventions at the group level) reports during the course of 10 treatment s...

BACKGROUND We investigated the efficacy of novel thrombin fragment TP508 on ischemia-reperfusion injury using a porcine model of type 1 diabetes mellitus. METHODS AND RESULTS Alloxan-induced diabetic male Yucatan swine underwent 60 minutes of mid-left anterior descending coronary artery occlusion, followed by 120 minutes of reperfusion. Fifty minutes into ischemia, animals received either pla...

The aim of this study is the investigation adsorption and corrosion behaviors 2,4-Diamino-6-methly-1,3,5-triazine (2-DMT) on mild steel (MS) in 0.5 M HCI solution using many experimental theoretical studies such as potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), linear polarization resistance (LPR), isotherm, potential zero charge (PZC), scanning electron (SEM), atom...

Experiential classes that use dance/movement as the primary means of learning are universal in therapy (DMT) graduate education programs United States. Yet, there have been no studies to determine what competencies develop movement based experiential DMT education. This is a report qualitative study used thematic analysis identify students from (MBEL). Competencies identified this were compared...

This study was aimed at determining the effect of type 1 diabetes mellitus on bilirubin excretion, and to ascertain the impact of treatment with crude Aloe vera gel on bilirubin excretion. The phyto-constituents and median lethal dose of the plant material were determined before administration. Forty albino wistar rats were randomly assigned into four groups of 10 rats each as follows; control ...