conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...

Metabolic syndrome is a complex of metabolic, hormonal and clinical disorders. The aim the research was to consider main markers metabolic disorders in body fish on model toxic damage zebrafish (20 males 20 females) aged 2-3 months. Before start experiment, were divided into two parity groups. Indicators monitored daily according standard methods. quality habitat corresponded GOST 15.372 - 87, ...

background and objective type 2 diabetes mellitus is a chronic, progressive illness that causes considerable morbidity and mortality. despite recent technical advances in therapy, more people are using alternative therapies. in this study evaluated the effect of sodium metavanadate on glucose levels and lipid profile in type 2 diabetes mellitus patients.   methods this is a randomized, controll...

The sugar transporter GLUT2, present in several tissues of the gut-brain axis, has been reported to be involved in the control of food intake. GLUT2 is a sugar transporter sustaining energy production in the cell, but it can also function as a receptor for extracellular glucose. A glucose-signaling pathway is indeed triggered, independently of glucose metabolism, through its large cytoplasmic l...

Abstract Starch,as the main source of carbohydrates in diet, provides energy for various activities body. Different types and structures starch lead to variations digestion absorption, thereby affecting blood glucose levels lipid metabolism Resistant (RS) has gained much attention because its unique properties; it is not digested small intestine but ferments large produces short-chain fatty aci...

BACKGROUND Myocardial energy metabolism is a strong predictor of postoperative cardiac function. This study profiled the metabolites and metabolic changes in the myocardium exposed to sevoflurane, propofol, and Intralipid and investigated the underlying molecular mechanisms. METHODS Sevoflurane (2 vol%) and propofol (10 and 100 microM) in the formulation of 1% Diprivan (AstraZeneca Inc., Miss...

This presentation will review highlights from the 12th International Workshop on Adverse Drug Reactions and Co-morbidities in HIV that will be held in London on 4-6 November 2010. As in the past, the meeting will consist of plenary lectures by experts from outside the field of HIV medicine as well as oral presentations and posters selected from abstracts submitted by attendees. The plenary spea...

1. Abstract 2. Introduction 3. Discussion 3.1. ABC lipid transporters 3.1.2. Macrophage ABC lipid transporters 3.1.3. ABC transporter mediated lipid export from the liver 3.2. ABCA1 is a key regulator of HDL metabolism and cellular cholesterol and phospholipid export 3.2.1. ABCA1 mediated cholesterol trafficking and caveolae 3.2.2. ABCA1 and NPC1: two major regulators of cellular cholesterol tr...

Many studies have revealed that gut microbes modulate host metabolism. In this study, we characterized the therapeutic effects of a novel commensal Luoshenia tenuis against metabolic disorders. First, by in silico analysis, demonstrated was prevalent in microbiomes healthy humans but were depleted specifically obesity cohorts. Further vitro cultivation L. produced short cha...

Protease inhibitor (PI) may cause abnormal glucose metabolism, abnormal lipid metabolism, and metabolic syndrome in HIV-infected adults but less well studied in Asian adolescents. This cross-sectional study evaluated anthropometric factors, oral glucose tolerance test, and lipid profiles of perinatally HIV-infected Thai adolescents who had received PI-based antiretroviral therapy for at least 6...