A remarkable characteristic of nutritional homeostatic mechanisms is the breadth of metabolite concentrations to which they respond, and the resolution of those responses; adequate but rarely excessive. Two general ways of achieving such exquisite control are known: stoichiometric mechanisms where increasing metabolite concentrations elicit proportionally increasing responses, and the actions o...

BACKGROUND Lung sequestration is a rare congenital pulmonary disorder and is usually diagnosed in children with recurrent pulmonary infections. Lung sequestrations are not commonly found to be a cause of respiratory symptoms in adults. OBJECTIVES It was the aim of this study to show that pulmonary sequestration is rare in advanced age and can be accompanied by severe pulmonary symptoms. MET...

Partial splenectomy was carried out in four children with homozygous sickle cell disease and eight children with sickle cell beta thalassaemia. It was performed in order to preserve splenic contribution to the host defence against infections while suppressing hypersplenism or the risk of recurrence of acute splenic sequestration. Indications for this surgical operation were acute splenic seques...

Economic impacts of agricultural carbon sequestration involve direct costs of sequestration management adoption as well as a variety of indirect costs and benefits. The nature and significance of these impacts are discussed. Spatial and temporal heterogeneity in agriculture is identified as an influential factor. Techniques to estimate the cost of agricultural carbon sequestration are briefly r...

Deglaciation of the Laurentide Ice Sheet in North America was accompanied by sequestration of organic carbon in newly exposed soils. The greatest rate of land exposure occurred around 12,000 to 8,000 years ago, and the greatest increase in the rate of carbon sequestration by soils occurred from 8,000 to 4,000 years ago. Sequestration of carbon in deglaciated peat lands continues today, and a st...

in this work we solve the set of hydrodynamical equations for accretion disks in the spherical coordinates (r,θ,ϕ) to obtain the explicit structure along θ direction. we study a two-dimensional advective accretion disc in the presence of thermal conduction. we find self-similar solutions for an axisymmetric, rotating, steady, viscous-resistive disk. we show that the global structure of an advec...

Sequestration of malaria-parasite-infected erythrocytes in the microvasculature of organs is thought to be a significant cause of pathology. Cerebral malaria (CM) is a major complication of Plasmodium falciparum infections, and PfEMP1-mediated sequestration of infected red blood cells has been considered to be the major feature leading to CM-related pathology. We report a system for the real-ti...

Preconditioning enables endogenous protection to repeated myocardial ischemia. However, the effect of preconditioning on beta1 adrenergic receptor (AR) signal remains controversial. We have recently developed receptor assay system using whole cells, in which overexpressed cell surface beta ARs can be readily quantitated without disrupting the cell. Using this technique, we examined the effects ...

The sequestration of Plasmodium falciparum-infected red blood cells (irbcs) in the microvasculature of organs is associated with severe disease; correspondingly, the molecular basis of irbc adherence is an active area of study. In contrast to P. falciparum, much less is known about sequestration in other Plasmodium parasites, including those species that are used as models to study severe malar...

Pulmonary sequestration and congenital broncho-esophageal fistula are both rare malformations; nonetheless, in the presence of recurrent pulmonary infection, the possibility that one or the other may be involved should not be disregarded. To our knowledge, the concurrence of intralobar pulmonary sequestration and congenital broncho-esophageal fistula is very rare. Herein, we report a case of in...