BACKGROUND Despite reports in the literature that both leisure-time physical activity (LTPA) and commuting physical activity (CPA) can promote health benefits, the literature lacks studies comparing the associations of these domains of physical activity with cardiovascular risk scores. OBJECTIVE To investigate the association between LTPA and CPA with different cardiovascular risk scores in t...

background: this study aims to investigate the effect of antioxidants supplement on clinical outcomes and antioxidant parameters in rheumatoid arthritis (ra). methods: the pre‑post study was conducted on 40 female patients with ra in 12 weeks that taken daily one “selenplus” capsule contained 50 μg selenium, 8 mg zinc, 400 μg vitamin a, 125 mg vitamin c, and 40 mg vitamin e. about 5 ml venous b...

background: nonalcoholic fatty liver disease (nafld) is the most common cause of chronic liver disease in the world. although some studies have been conducted about dietary intakes of these patients, but the results are inconsistent. the aim of this study was to survey all macronutrients and micronutrients included in dietary intake of these patients for better understanding the factors influen...

background: although physical activity (pa) has long been associated with cardiovascular disease (cvd), assessment of pa status has never been used as a part of cvd risk prediction tools. the aim of the present work was to examine whether the inclusion of pa status in a cvd risk model improves its predictive accuracy. methods: data from the 10‑year follow‑up (2002–2012) of the n = 2020 particip...

background: sandhoff disease is an autosomal recessive disorder caused by β-hexosaminidase deficiency and accumulation of gm2 ganglioside resulting in progressive motor neuron manifestations and death from respiratory failure and infections in infantiles. pathogenic mutations in hexb gene were observed which leads to enzyme activity reduction and interruption of normal metabolic cycle of gm2 ga...

parkinson's disease is a degenerative disorder of the central nervous system. the motor symptoms of parkinson's disease result from the death of dopamine-generating cells in the substantia nigra, a region of the midbrain the cause of this cell death is unknown. homocysteine (hcy) is a non-protein amino acid. it is a homologue of the amino acid cysteine. the elevated levels of homocysteine in pl...

pemphigus is a rare autoimmune blistering disease with different phenotypes. the evaluation of therapeutic interventions requires a reliable, valid and feasible to use measurement. however, there is no gold standard to measure the disease activity in clinical trials. in this study we aimed to introduce the pemphigus vulgaris activity score (pvas) measurement and to assess the convergent validit...

OBJECTIVE To 1) describe the distribution of patient global assessment (PtGA) scores of disease activity in patients with granulomatosis with polyangiitis (GPA; Wegener's), 2) explore the discordance between PtGA scores and physician global assessment (PhGA) scores of disease activity, and 3) explore whether PtGA scores during disease remission are associated with future disease relapse. METH...