نتایج جستجو برای: disease activity
تعداد نتایج: 2478757 فیلتر نتایج به سال:
Background and Objective: Systemic lupus erythematosus is an autoimmune disease and its prevalence in Iran is estimated to be 40 in 100,000 people. The psychological manifestations are common in patients with clinical manifestations. The purpose of this study was to investigate the effectiveness of MBRI and cognitive-behavioral therapy (CBT) on disease activity, quality of life and self-efficie...
nowadays, the development of anti cancer drugs is an important subject in pharmacology. bisphosphonates (b.p) are a great choice for design and production of the types of drugs which not only could perform as anti cancer agents but also could inhibit the function of acetyl cholinesterase (ache). ache hydrolyzes the acetylcholine (which is a neurotransmitter in nervous system) using the oh in i...
Background and objectives: Hesperetin flavanone is a natural bioflavonoid found abundantly in citrus fruits with antioxidant and anti-inflammatory properties. Nano sizing techniques improve the bioavailability of poorly soluble drugs such as hesperetin. Main feature of Parkinson's disease is the degeneration of dopaminergic neurons in the substantia nigra. The rate of oxidative...
background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...
Background & Aims: Alzheimer’s disease is the most common form of dementia which it destroyed memory and thinking skills slowly. There is no cure for the disease and it leads to death eventually. Proline rich peptide (PRP -1) is produced from neurosecretory cells of hypothalamus that has large spectrum of biological action on immune and nervous system . The Aβ1-42 is more effective in the de...
introduction: the regulation of neuroendocrine axis is one of the most important goals in the treatment of rheumatoid arthritis. disease modifying drugs such as chloroquine with low dose steroid is the first choice in clinical practice by some physicians. this combination therapy is evaluated by this study. methods: this survey is a prospective study on furty patients. variables for determining...
Hesperetin (Hst) is a well-known bioflavonoid, has low bioavailability. Hesperetin nanoparticles (Nano-Hst) enhance its bioavailability. Nano-Hst were not explored for their potential therapeutic activities in Alzheimer’s disease (AD). Hence, the present study was performed to evaluate the protective effect of Nano-Hst in comparison to free Hesperetin on against intracerebroventricular in...
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