Signaling centers or organizers play a key role in axial patterning processes in animal embryogenesis. The function of most vertebrate organizers involves the activity of secreted antagonists of bone morphogenetic proteins (BMPs) such as Chordin or Noggin. Although BMP homologs have been isolated from many phyla, the evolutionary origin of the antagonistic BMP/Chordin system in organizer signal...

Today's world's societies are becoming more and more dependent on open networks such as the Internet where commercial activities, business transactions and government services are realized. This has led to the fast development of new cyber threats and numerous information security issues which are exploited by cyber criminals. The inability to provide trusted secure services in contemporary com...

Synaptic adhesion molecules control neuronal synapse development. In this issue of Neuron, Siddiqui et al. (2013) and de Wit et al. (2013) demonstrate that LRRTM4, a postsynaptic adhesion molecule, trans-synaptically interacts with presynaptic heparan sulfate proteoglycans (HSPGs) to promote synapse development.

The FH proteins, defined by the presence of 'formin homology' regions, are important for a number of actin-dependent processes, including polarized cell growth and cytokinesis. They are large, probably multi-domain, proteins and their function may be in part mediated by an interaction with profilin.

Exchanging ideas with like-minded, enthusiastic people interested in the same topic is crucial for the advancement of a scientist's career. Several Regional Student Groups (RSGs) of the International Society for Computational Biology (ISCB) Student Council have cooperated in the last six years to organize scientific workshops and conferences. With motivated students, it is possible to create a ...

Pattern formation in muscle development is often mediated by special cells called muscle organizers. During metamorphosis in Drosophila, a set of larval muscles function as organizers and provide scaffolding for the development of the dorsal longitudinal flight muscles. These organizers undergo defined morphological changes and dramatically split into templates as adult fibers differentiate dur...

Drawing from the literature in Intercultural and New Media Studies (INMS), this study explores the SlutWalk social movement, a transnational movement of protest marches. The author conducted interviews with seven SlutWalk organizers from various cities in the United States to understand what culture SlutWalk organizers are fostering through their work and the role of new media communication in ...