STUDY DESIGN A kinematic analysis of cervical intervertebral disc deformation during simulated whiplash using the whole cervical spine with muscle force replication model was performed. OBJECTIVES To quantify anulus fibrosus fiber strain, disc shear strain, and axial disc deformation in the cervical spine during simulated whiplash. SUMMARY OF BACKGROUND DATA Clinical studies have documented...

It has previously been demonstrated that disc puncture in the rat induced changes in grooming and wet dog shakes, two behavioral changes that may be linked to discomfort and neuropathic pain. In this study the aim was to separate the effects of disc injury and the epidural presence of nucleus pulposus. Following anesthesia, the L4-5 disc was exposed using a dorsal approach. Ten rats received a ...

The X-ray spectra of Galactic binary systems dominated by a quasi-thermal component (disc dominated or high/soft state) are well described by a standard ShakuraSunyaev disc structure down to the last stable orbit around the black hole. This is not the case in the very high (or steep power law) state, where the X-ray spectra show both a strong disc component and strong, steep tail to higher ener...

In a cold dark matter ( CDM) cosmology, the Milky Way accretes satellites into the stellar disc. We use cosmological simulations to assess the frequency of near disc plane and higher inclination accretion events, and collisionless simulations of satellite mergers to quantify the final state of the accreted material and the effect on the thin disc. On average, a Milky Way-sized galaxy has three ...

OBJECTIVE The aim of this study was to predict the relationship between the symptomatic disc herniation level and the osteophyte level or decreased disc height in patients with cervical disc herniation. METHODS Between January 2011 and December 2012, 69 patients with an osteophyte of the cervical spine underwent surgery at a single center due to soft cervical disc herniation. Data including s...

The accumulation of senescent disc cells in degenerative intervertebral disc (IVD) suggests the detrimental roles of cell senescence in the pathogenesis of intervertebral disc degeneration (IDD). Disc cell senescence decreased the number of functional cells in IVD. Moreover, the senescent disc cells were supposed to accelerate the process of IDD via their aberrant paracrine effects by which sen...

BACKGROUND Magnetic Resonance Imaging (MRI) is considered the mainstay imaging investigation in patients suspected of lumbar disc herniations. Both imaging and clinical findings determine the final decision of surgery. The objective of this study was to assess MRI observer variation in patients with sciatica who are potential candidates for lumbar disc surgery. METHODS Patients for this study...

STUDY DESIGN Review and reinterpretation of existing literature. OBJECTIVE To suggest how intervertebral disc degeneration might be distinguished from the physiologic processes of growth, aging, healing, and adaptive remodeling. SUMMARY OF BACKGROUND DATA The research literature concerning disc degeneration is particularly diverse, and there are no accepted definitions to guide biomedical r...

Bilateral optic disc edema in a diabetic patient may be caused by diabetic papillopathy. We herein report on a patient with bilateral optic disc drusen simulating diabetic papillopathy. A 55-year-old patient with type 2 diabetes presented with decreased vision of 1-month. Diabetic papillopathy was initially considered as there was disc edema in both eyes with focal hemorrhages at the disc margi...

Optic disc pit and optic nerve coloboma are examples of congenital optic disc abnormalities. Although optic nerve coloboma can be inherited in an autosomal dominant fashion, no conclusive link has been found in the case of optic disc pit as an autosomal dominant disease. We describe two cases: a daughter with an optic disc pit complicated by maculopathy and her mother with a congenitally abnorm...