نتایج جستجو برای: dipeptidyl peptidase iv

تعداد نتایج: 187377  

Journal: :The Biochemical journal 2001
D Riemann G H Hansen L Niels-Christiansen E Thorsen L Immerdal A N Santos A Kehlen J Langner E M Danielsen

Membrane peptidases play important roles in cell activation, proliferation and communication. Human fibroblast-like synoviocytes express considerable amounts of aminopeptidase N/CD13, dipeptidyl peptidase IV/CD26, and neprilysin/CD10, transmembrane proteins previously proposed to be involved in the regulation of intra-articular levels of neuropeptides and chemotactic mediators as well as in adh...

Journal: :The Journal of biological chemistry 1999
M N Pangalos J M Neefs M Somers P Verhasselt M Bekkers L van der Helm E Fraiponts D Ashton R D Gordon

Hydrolysis of the neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) by N-acetylated alpha-linked acidic dipeptidase (NAALADase) to release glutamate may be important in a number of neurodegenerative disorders in which excitotoxic mechanisms are implicated. The gene coding for human prostate-specific membrane antigen, a marker of prostatic carcinomas, and its rat homologue glutamate carboxypep...

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