Fluorescence molecular tomography (FMT) has potential of providing high contrast images for breast tumor detection. Computational phantom provides a convenient way to a wide variety of fluorophore distribution configurations in patients and perform comprehensive evaluation of the imaging systems and methods for FMT. In this study, a digital breast phantom was used to compare the performance of ...

The GATE 6.1 Monte Carlo simulation platform based on the GEANT4 toolkit is in constant 15 improvement for dosimetric calculations. Here, we explore its use for calculating internal absorbed dose distribution in mice for the treatment of malignant melanoma after injection of a new specific radiopharmaceutical labeled with iodine 131. We estimate the dosimetric accuracy of GATE 6.1, by calculati...

Objective: Different categories are available for estimating of radiation dose. Radioisotopes with the same energy and almost the same physical properties have similar effects. Monte Carlo technique is a computerized method based on mathematical simulation of physical processes. The main purpose of this study is to show that beta particles are not able to penetrate deep into the water. also dif...

Introduction: Gamma Knife is an instrument specially designed for treating brain disorders. In Gamma Knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. The tumor is placed at the isocenter and is treated by the emitted gamma rays. Therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surroun...

Introduction Application of near-infrared absorbing nanostructures can induce hyperthermia, in addition to providing more efficient  photothermal effects. Gold-gold sulfide (GGS) is considered as one of these nanostructures. This study was performed on a tissue-equivalent optical-thermal phantom to determine the temperature profile in the presence and absence of GGS and millisecond pulses of a ...

Digital breast tomosynthesis (DBT) is an emerging technique that allows for slices parallel with the detector to be constructed through the breast, as opposed to two dimensional mammography. Present phantoms for use on mammography systems are two dimensional in nature and focus mainly on differences in contrast. Since tomosynthesis is a three-dimensional-technique, a suitable phantom for use on...

An approach reported recently by Alexandrov et al. 1 on optical scatter imaging, termed digital Fourier microscopy (DFM), represents an adaptation of digital Fourier holography to selective imaging of biological matter. Holographic mode of recording of the sample optical scatter enables reconstruction of the sample image. Form-factor of the sample constituents provides a basis for discriminatio...