BACKGROUND Lead (Pb) exposure may influence the plasma concentration of homocysteine, a one-carbon metabolite associated with cardiovascular and neurodegenerative diseases. Little is known about the associations between Pb and homocysteine over time, or the potential influence of dietary factors. OBJECTIVES We examined the longitudinal association of recent and cumulative Pb exposure with hom...

Protein-based drugs are the fastest growing class of drugs for the treatment of disease in humans and other animals. However, the current method of producing proteins for pharmaceutical application is predicted to fall short because of population growth and demographic trends. This study characterized human dietary risks using quantitative risk assessment techniques for three pharmaceutical pro...

Children's dietary exposure to metals has received limited attention in Australia. This study undertook a market basket survey and analysed 253 food and beverages for metals. These data were used in conjunction with recent average diet data for children in Western Australia to model dietary metals exposure, with mean metals intakes calculated for boys and girls aged 8, 12, 13 and 16 years. Resu...

As part of a large pilot investigation of multimedia exposure to several classes of environmental contaminants, the National Human Exposure Assessment Survey (NHEXAS)-Maryland study, we collected 388 semiquantitative food checklists and duplicate diet solid food samples, analyzed for arsenic, cadmium, chromium, and lead concentrations, from 80 individuals in Maryland in 1995-1996 in a repeated ...

As the prevalence of obesity is increasing, many people resort to dieting to achieve a healthy body weight. Such dietary restraint has been suggested to cause counterproductive effects leading to disinhibited eating. However, it is more likely that dietary restraint is a by-product of previous difficulties in weight control and disinhibited eating. If so, disinhibition should be related more st...

Per- and polyfluorinated alkyl substances (PFAS) can be found in food contact materials (FCMs). Therefore, migration into occurs contributes to human dietary exposure. Identification minimization of possible exposure-pathways these omnipresent potentially toxic chemicals are important mitigate health risks. Nonetheless, risk assessment procedures mostly limited considering the final PFAS concen...