Background: Endometriosis is an enigmatic disease that affects approximately 10% of women reproductive age and almost 50% with endometriosis experience infertility. These symptoms dysmenorrhea, premenstrual pain, dyspareunia, infertility, but many affected are asymptomatic. Objective: To analyse the clinical pregnancy rate after treating mild minimal causing infertility dienogest (2 mg) or by s...

BACKGROUND The purpose of this study was to quantify the impact of estradiol-valerate/dienogest (E(2)V/DNG; Qlaira(®)/Natazia(®)) on work productivity and activities of daily living in European and Australian women with heavy menstrual bleeding. METHODS Women aged 18-54 years with a confirmed diagnosis of heavy menstrual bleeding and no recognizable pathology were recruited across nine Europe...

The aim of this study was to evaluate the effect of selective and short-term sex hormone modifications on ghrelin levels in normal-weight eugonadal men undergoing hormonal contraceptive treatments. Seven men received an oral progestin [cyproterone acetate (CPA) or dienogest (DNG)] 10 mg/day for 3 weeks (CPA-DNG group), 7 CPA orally 5 mg/day in association with testosterone enanthate (TE) im 200...

OBJECTIVE To review the literature on the most recent progestogens to be developed, to provide clinical comparisons with older progestogens and to look at the potential of products not yet marketed. DATA SOURCES Searches of Medline and Popline together with requests for bibliographies from the Population Council, Wyeth-Ayerst Research and Schering Health Care. STUDY SELECTION Information fr...

Considerable advances have been made in hormonal contraception in recent years, geared at maximizing compliance and minimizing discontinuation. In oral contraceptive (OC) formulations, the estrogenic component, generally ethinyl estradiol (EE), has been reduced significantly and newer progestins like dienogest and drospirenone (DRSP), compounds with different molecular structures, have been int...

Combined oral contraceptives In the UK combined oral contraceptives (COCs), containing both oestrogen and progestogen, are the most popular method of contraception for women under age 30. The most common oestrogen used is ethinyl estradiol (EE), in doses between 20 and 35μg. Progestogens are classified according to their steroid structure and the timing of their introduction on to the market. T...