1.1 Diarrhoea is a global problem Diarrhoea is one of the most common causes of morbidity and mortality in children worldwide. The word diarrhoea is derived from the Greek "diarrhoia", meaning to flow through. In clinical terms, diarrhoea refers to either an increased stool frequency or a decreased stool consistency, typically a watery quality. The World Health Organization (WHO) defines a case...

OBJECTIVE To evaluate the effect on morbidity and mortality of providing daily zinc for 14 days to children with diarrhoea. DESIGN Cluster randomised comparison. SETTING Matlab field site of International Center for Diarrhoeal Disease Research, Bangladesh. PARTICIPANTS 8070 children aged 3-59 months contributed 11 881 child years of observation during a two year period. INTERVENTION Chi...

OBJECTIVE The aim of this literature review is to identify the role of probiotics in the management of enteral tube feeding (ETF) diarrhoea in critically ill patients. BACKGROUND Diarrhoea is a common gastrointestinal problem seen in ETF patients. The incidence of diarrhoea in tube fed patients varies from 2% to 68% across all patients. Despite extensive investigation, the pathogenesis surrou...

BACKGROUND Antibiotic associated diarrhoea complicates 5-39% of courses of antibiotic treatment. Major risk factors are increased age and admission to hospital. Of particular importance is C. difficile associated diarrhoea which occurs in about 4% of antibiotic courses and may result in severe illness, death and high healthcare costs. The emergence of the more virulent 027 strain of C. difficil...

BACKGROUND Rates of travel-related diarrhoea vary from 8% to 50% depending on the country visited. Travellers' diarrhoea has social, health and economic costs. The impact of these may be reduced by relevant pre-travel advice. Little is known of the effect of pre-travel advice on the incidence of diarrhoea among travellers abroad. AIM To determine the 'true' attack rate of travellers' diarrhoe...

We report a case of a patient with late-onset primary lymphangiectasia whose persistent diarrhoea was successfully managed with octreotide. A 63 year-old man visited our clinic with a complaint of worsening general edema. Gastrointestinal endoscopy revealed typical whitish jejunal villi, which suggested primary intestinal lymphangiectasia. Despite a diet, supplemented with medium-chain triglyce...

BACKGROUND To describe spatiotemporal patterns of diarrhoea in Bhutan, and quantify the association between climatic factors and the distribution and dynamics of the disease. METHODS Nationwide data on diarrhoea were obtained for 2003 to 2013 from the Health Information and Management System (HIMS), Ministry of Health, Bhutan. Climatic variables were obtained from the Department of Hydro Met ...

High levels of faecal alpha-1-antitrypsin were found in children suffering from acute rotavirus diarrhoea and in children with diarrhoea in whom no microbial pathogen could be established. The results suggest that transient protein-losing enteropathy is common in acute childhood diarrhoea and may influence the outcome of the disease.

PURPOSE/OBJECTIVE The evolving Non-Governmental Organization (NGO) sector in Bangladesh provides health services directly, however some NGOs indirectly provide services by working with unlicensed providers. The primary objective of this study was to examine the impact of NGO training of unlicensed providers on diarrhoea management and the scale up of zinc treatment in rural populations. METHO...

INTRODUCTION Diarrhoea among children under-five is a serious public health problem in many developing countries, including Nepal. This study aimed to examine the association between health service utilization and diarrhoea management approaches among children under-five years in Nepal. METHODS The combined 2001, 2006 and 2011 Nepal Demographic and Health Survey (NDHS) data sets were examined...