Case 1: A 4-year-old girl presented to our emergency department (ED) during the height of summer with 5 days of left-sided facial droop, which spared the forehead. The patient also complained of severe fatigue, 1 week of frontal headaches, urinary retention, intermittent erythematous rash around her eyes and behind her knees, and an increase in night terrors. Three days before admission, she wa...

Autoimmune lymphoproliferative syndrome (ALPS) is an uncommon nonmalignant lymphoproliferative disease which is characterized by chronic, persistent or recurrent lymphadenopathy, splenomegaly, hepatomegaly, immune cytopenia , hypergammaglobinemia and increased risk of lymphoma. We report a 2-year old boy with hepatosplenomegaly as first presentation. Petechial and purpuric rashes with massive c...

A 7-month-old male infant was brought to this department by his parents without referral from his family doctor. For 6 months he had suffered from a rash in the napkin area which was resistant to various treatments. These had included a variety of 'barrier' creams, topical antifungal agents and Hydrocortisone ointment. Recently the parents had become concerned by the development of two lesions ...

Coxsackie viruses are enteroviruses most common in children. Coxsackie B viral infections often present with biphasic fever, headache, pharyngitis, nausea/vomiting, diarrhea and a maculopapular rash that spares the palms and soles. These clinical features may be present in other viral infections. We present a case of a hospitalized adult with rash and fever with highly elevated ferritin levels ...

In sections of control and normal skin, the nuclei of the epithelial cells were often indented by the cell protoplasm, giving them an appearance similar to those indented by Mallory's bodies. It would seem that if these bodies of Mallory's were protozoa they would have been found in the sections from both the living and the dead skin of scarlet-fever and measles, as they were present in the bli...

History: A seven-month-old, developmentally normal girl – born at term with birth weight of 2.5 kg to a nonconsanguineously married couple – presented with fever and rash for 11⁄2 months. The illness started with generalized erythematous, maculopapular rash involving the flexural areas, scalp and trunk, along with intermittent fever. The rash subsided over 15 days leaving behind a dry, scaly sk...

Syphilis in preschoolers is rarely described in current medical literature, despite the rise in syphilis in both the adult and the pediatric populations during the past decade. Since that time, 3 children between 3 and 4 years of age have been diagnosed with syphilis at the Children's Hospital of Philadelphia. The presentations and clinical manifestations of syphilis in these 3 children are des...

Gianotti-Crosti syndrome (GCS) is a sporadic dermatosis affecting mainly children. It is characterized by multiple, confluent, monomorphic and pruritic pink to red-brown papules or papulovesicles, distributed symmetrically on the face, extensor surfaces of the extremities and buttocks, commonly sparing the trunk, palms and soles. This can be preceded by a viral infection, and may be accompanied...

Case Reports Case 1. A female, aged five years, was brought to the out-patient department at the Royal Hospital, Wolverhampton, on February 24, 1943, on account of purpura, and was admitted at once. There was no previous history of illness. The present ilhlss began suddenly on February 17, 1943, with pains in the legs (which lastd for one week). Twodayslatertherewasswellingofbothankles which la...

Acquired palsy of the lateral rectus presents with horizontal diplopia and has a broad differential. Herpes zoster ophthalmicus- (HZO) related cranial nerve palsy is a transient and self-limiting condition. Systemic antiviral treatment is administered in order to prevent sight-threatening complications. In suspected cases, zosteriform rash should be questioned. One should keep in mind that acqu...