BACKGROUND Cardiovascular disease is a frequent cause of death in peritoneal dialysis patients. Biocompatible peritoneal dialysis solutions with neutral pH have been anticipated to reduce cardiovascular disease more than conventional peritoneal dialysis solutions with low pH, but it remains unclear which factors at peritoneal dialysis initiation increase cardiovascular risk in patients using bi...

In this study, we prepared all-trans retinoic acid (ATRA)-encapsulated, surfactant-free, PLGA nanoparticles. The nanoparticles were formed by nanoprecipitation process, after which the solvent was removed by solvent evaporation or dialysis method. When a nanoparticle was prepared by the nanoprecipitation solvent evaporation method, the nanoparticles were bigger than the nanoparticles of the nan...

An ever-increasing number of patients have to undergo regular renal dialysis to compensate for acute or chronic renal failure. The adequacy of the treatment has a profound effect on patients' morbidity and mortality. Therefore, it is necessary to assess the delivered dialysis dose. For the quantification of the dialysis dose, two parameters are most commonly used, namely the K(t)/V value (norma...

INTRODUCTION Coagulation-free dialysis, also commonly known as "heparin-free" dialysis, can be a challenging procedure as it increases the risk of clotting the dialysis circuit. Utilizing a better saline flushing technique can lead to improved patient outcomes as well as huge financial benefits to the health institution. The purpose of this study was to compare the effectiveness of continuous s...

peritoneal dialysis is an established form of renal replacement therapy used in many patients with end-stage renal disease. the key to a successful chronic peritoneal dialysis is a permanent and safe access to the peritoneal cavity. this study was conducted in order to evaluate the catheter survival and its related factors in imam khomeini hospital. a total of 80 catheters were inserted into 69...

BACKGROUND In survival analysis, patients on peritoneal dialysis are confronted with three different outcomes: transfer to hemodialysis, renal transplantation, or death. The Kaplan-Meier method takes into account one event only, so whether it adequately considers these different risks is questionable. The more recent competing risks method has been shown to be more appropriate in analyzing such...

Risk assessments performed at the conceptual design phase of a product may offer the greatest opportunity to increase product safety and reliability at the least cost. This is an especially difficult proposition, however, as often the product has not assumed a physical form at this early design stage. This paper introduces the Risk in Early Design (RED) method, a method for performing risk asse...