Leptomeningeal metastasis is known to occur as an initial presentation in solid tumors. The of meningeal symptoms before the diagnosis primary tumor seen 10-20% cases. Though sophisticated radiological imaging available, Cerebrospinal Fluid (CSF) analysis for cells remains gold standard method diagnosis. Incidence brain from carcinoma breast about 3-8% only.
 We present a case young female...

background and importance: the coexistence of pituitary adenoma and another type of brain tumor is a very rare clinical scenario. even though such a presentation can be an incidental event but the possible pathogenesis of coexistence of different lesions in the sella and suprasellar region has not yet been elucidated. case presentation: two cases of concomitant sellar and suprasellar region tum...

Brain tumor is a very harmful disease for human being. A tumor is a mass of tissue that's formed by an accumulation of abnormal cells. The location of tumors in the brain is one of the factors that determine how a brain tumor effects an individual's functioning. Image processing is an active research area in which medical image processing is a highly challenging field. For medical diagnosis of ...

gene expression profiling of ovarian carcinoma tissues has shown an increase of four-fold expression of sort1 gene. sortilin 1 (ntr-3) is a 95-100 kda protein normally expressed in heart, brain, placenta, skeletal muscle, spinal cord, thyroid, and testis. however, its expression has never been reported in normal ovary. here, we report expression of sortilin 1 in ovarian carcinoma tissues both a...

objective(s): in order to grow cells in a three-dimensional (3d) microenvironment, self-assembling peptides, such as puramatrix, have emerged with potential to mimic the extracellular matrix. the aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma st...

objective(s): the study objective was to assess the diagnostic performance of positron emission tomography (pet) for gliomas using the novel tracer 18f-fluciclovine (anti-[18f]facbc) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.methods: anti-[18f]facbc was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by pet...

BACKGROUND Improvements in brain tumor treatments have led to an increase in the number of young women with brain tumors who are now considering pregnancy. The aim of this study is to evaluate the influence of pregnancy on brain tumor biology. METHODS In this institutional review board-approved retrospective study, we searched the institution's database for patients with glial brain tumors wh...

Glioblastoma Targeted Therapy In article number 2209579, Wang and co-workers report a near-infrared persistent luminescence nanoparticle for the diagnosis targeted therapy of glioblastoma (GBM). GBM cell membrane (GCM) coating chlorotoxin enhanced blood-brain barrier (BBB) penetration targeting tumor-homing GBM. This study offers an example highly promising drug carriers precise central nervous...