نتایج جستجو برای: di 2 ethylhexyl phthalate

تعداد نتایج: 2747168  

Journal: :Environmental research 2008
Shanna H Swan

After briefly discussing human exposure to phthalates--diesters of 1,2-benzenedicarboxylic acid (phthalic acid)--this article first presents recent findings from the Study for Future Families, a multi-center pregnancy study in which the human analogue of the phthalate syndrome was first identified. This is one of an increasing number of studies that have investigated human endpoints in relation...

2012
Katherine E. Kelley Sonia Hernández-Díaz Erica L. Chaplin Russ Hauser Allen A. Mitchell

BACKGROUND In animal studies, some ortho-phthalates, including di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP), have been shown to be reproductive and developmental toxicants. Human studies show widespread population exposure to background levels of phthalates. Limited evidence suggests that particularly high exposure levels may result from orally ingested medicinal products co...

2008
Jennifer J. Adibi Robin M. Whyatt Paige L. Williams Antonia M. Calafat David Camann Robert Herrick Heather Nelson Hari K. Bhat Frederica P. Perera Manori J. Silva Russ Hauser

BACKGROUND Although urinary concentrations of phthalate metabolites are frequently used as biomarkers in epidemiologic studies, variability during pregnancy has not been characterized. METHODS We measured phthalate metabolite concentrations in spot urine samples collected from 246 pregnant Dominican and African-American women. Twenty-eight women had repeat urine samples collected over a 6-wee...

Journal: :Occupational and environmental medicine 2005
R Hauser A M Calafat

Correspondence to: Prof. Associate R Hauser, Occupational Health Program, Harvard School of Public Health, Building 1, Room 1405, 665 Huntington Avenue, Boston, MA 02115, USA; [email protected]. edu _________________________ T he diesters of 1,2-benzenedicarboxylic acid (phthalic acid), commonly known as phthalates, are a group of man-made chemicals with a wide spectrum of industrial applica...

2012
Ulla Nordström Joensen Hanne Frederiksen Martin Blomberg Jensen Mette Petri Lauritsen Inge Ahlmann Olesen Tina Harmer Lassen Anna-Maria Andersson Niels Jørgensen

BACKGROUND In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function. OBJECTIVES We aimed to provide estimates of the effects of phthalate exposure on reproductive hormone levels and semen quality in healthy men. METHODS A total of 881 ...

Journal: :American journal of epidemiology 2009
Jennifer J Adibi Russ Hauser Paige L Williams Robin M Whyatt Antonia M Calafat Heather Nelson Robert Herrick Shanna H Swan

Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer used in consumer and medical products that can cross the placenta, disrupt steroid hormone synthesis, and activate peroxisome proliferator-activated receptor gamma. The authors examined DEHP exposure in relation to the timing of labor in a pregnancy cohort study of 283 women recruited in 4 US states (California, Iowa, Minnesota, and Missouri) ...

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