One of the most important tasks operations manager are confronted with is to determine production quantities over a medium-size planning horizon such that demand is met, scarce production facilities are not overloaded and that the sum of holding and setup costs is minimized. For the single machine case the well-known Capacitated Lot-Sizing Problem (CLSP) has been proposed to determine minimum c...

In the process industry, both quality and consistency of mid-term planning and short-term scheduling are crucial. We propose a sequential approach consisting in three steps : planning, lot streaming-pegging, and scheduling. This paper focuses on the intermediate problem that consists in cutting up the planned production in several lots (lot streaming) and linking stocks, lots and demands by det...

Automated digoxin immunoassays with the Abbott TDx, Dade Stratus, and Du Pont aca were evaluated against an RIA similar to the Centers for Disease Control Candidate Reference Method. All three automated methods correlated poorly with the reference method. Particularly disconcerting were the falsely increased values (up to 0.6 micrograms/L) obtained by the Stratus for blank specimens. We discuss...

The objective of this research is to tackle the emerging problem of jointly determining theoptimal retail price, the replenishment cycle, and the cost of preservation technology investment from an integrated perspective among the supplier and the manufacturer. This paper deals an integrated single-manufacturer single-retailer supply chain model for deteriorating items under revenue sharing on p...

Lot-sizing and capacity planning are important supply chain decisions, and competition and cooperation affect the performance of these decisions. In this paper, we look into the dynamic lot sizing and resource competition problem of an industry consisting of multiple firms. A capacity competition model combining the complexity of time-varying demand with cost functions and economies os scale ar...

Despite considerable progress within wilderness and adventure therapy research over the last decade, researchers are still unable to precisely answer why, how, and for whom this treatment modality works. There is also a need for more knowledge regarding the circumstances under which the treatment does not appear to be effective. In this realist synthesis, we attempt to unpack this "black box" o...