results migration of cells started on the fifth day. as a result of this migration, most cells were located on the surface of the scaffold and formed epiderm-like structure and some penetrated into the scaffold. by day 25, cells which had penetrated into the scaffold had various destinies such as becoming elongated spindle-shaped cells and creating blood vessel-like structures. conclusions adm ...

background: considering the common origin of skin and peripheral nervous system, a tube of dermal layer of skin hypothetically can be an ideal conduit for nerve reconstruction. an experimental study performed to evaluate the nerve regeneration of efficacy into a dermal tube. methods: sixty male wistar rats were used. a 10 mm gap was produced in right sciatic nerves. in group a the autogenous ne...

to malignant melanoma. The exact cause is unknown. There may be hereditary factors, autosomal dominance or other multifactor determinants. Management depends upon size, location and malignant transformation. Surgical excision is the mainstay of treatment. Cultured epidermal autograph has been used successfully to cover postoperative large surface area defect. We report a one-day-old male child ...

A 76-year-old man with compressive optic neuropathy secondary to a retrobulbar mass was managed by orbitotomy and removal of the mass. The lesion proved histopathologically to be an unusual orbital melanoma with massive central necrosis. There was no histopathological evidence of congenital melanocytosis. Dermatological and systemic evaluation before and after orbital surgery revealed no eviden...

With increasing use of dermal fillers, more and more adverse effects are reported. The most devastating one is intravascular injection. We propose a novel needle prototype that allows physicians to prevent intravascular injection.