Chemical leukoderma occurs due to the toxic effect of a variety of chemical agents. Mechanisms include either destruction or inhibition of melanocytes. We report two male patients (36 and 51 years old) who presented with multiple hypopigmented macules and patches on the neck, wrist, and legs after exposure to dimethyl sulfate in a chemical industry. Physical examination revealed irregular depig...

A 21-year-old female presented with multiple hyperpigmented macules on the left side of the face of 17 years’ duration. Hyperpigmented macules were noticed on the left side of the cheek at the age of 4 years, which gradually progressed to involve the left half of the face, neck, chest and upper back. No history of photosensitivity was present. There was no history of epilepsy, mental retardatio...

A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disord...

The Bourneville-Pringle syndrome is an autosomal dominant neurocutaneous disorder characterized by the development of multiple hamartomas in various systems, especially brain, skin, retina, kidney, heart and lung. The case of a patient with brownish plaques on the forehead and temporal region, pink malar and chin papules, and hypopigmented macules on the back and trunk is described. The diagnos...

Nomenclature This pigmentary disorder is known by different names in various literatures. They are listed out here to avoid confusion. 1. Acquired bilateral nevus of Ota-like macules (ABNOM) 3, 10-13 2. Nevus fusco-caeruleus zygomaticus 4 3. Hori's nevus 10, 12,14 4. Acquired circumscribed dermal facial melanocytosis 5. In Taiwan, it is known as 褐藍色顴痣, which is translated from ''nevus fusco-cae...

Lichen planus pigmentosus-inversus is a rare variant of lichen planus pigmentosus. The eruption of lichen planus pigmentosus-inversus occurs mainly in the flexural regions and presents with brownish macules and patches. Here we describe the case of a 31-year-old Korean woman who presented with hyperpigmented lesions over her antecubital and popliteal area and groin. Physical examination reveale...