soon after successful results of balloon valvuloplasty in treatment of congenital pulmonary stenosis, use of this technique for relief of congenital aortic stenosis (as) was attempted in different parts of the world. with the purpose of assessment the value of valvuloplasty in comparison with surgical valvotomy in relief of congenital as, we retrospectively studied 115 patients with valvar as, ...

OBJECTIVES The objective is to present clinical outcomes of subglottic and tracheal stenosis treated by flexible bronchoscopic delivery of carbon dioxide (CO2) laser via laryngeal mask airway (LMA). METHODS All consecutive, nontracheotomy dependent cases of subglottic and tracheal stenosis treated endoscopically over a 4-year period were retrospectively reviewed. The surgical approach consist...

Angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers (ARBs) may induce an acute decrease of glomerular filtration rate (GFR) in the stenotic kidney in renal artery stenosis, but most patients tolerate these drugs well. We hypothesized that angiotensin-converting enzyme inhibitors/ARBs stabilize stenotic kidney function during prolonged treatment by conferring protective eff...

1. The participation of neural mechanisms in mediating the renin release induced by reduction of renal perfusion pressure was explored in anaesthetized cats by comparing renin release from the two kidneys, one acutely denervated and the other intact. 2. Suprarenal aortic stenosis of 10 min duration reduced renal perfusion pressure to 50 mmHg and halved blood flow to both kidneys, but cause a gr...

background: paraoxonase-1(pon1), a high-density lipoprotein (hdl) associated enzyme, is believed to contribute in the patho­genesis of coronary artery disease (cad). the aim of this study was to evaluate the association of pon1 promoter c (-107)t polymorphism with the extent of coronary artery stenosis in iranian patients. methods : the rflp analysis for determination of the c(-107)t genotype d...

giant left atria are defined as those measuring larger than 8 cm and are typically found in patients who have rheumatic mitral valve disease with severe regurgitation. enlargement of the left atrium may create compression of the surrounding structures such as the esophagus, pulmonary veins, respiratory tract, lung, inferior vena cava, recurrent laryngeal nerve, and thoracic vertebrae and lead t...

introduction:  the aim of this study was to compare the preventive effects of corticosteroids and curcumin on subglottic stenosis in an animal model.  materials and methods: twenty-one male german shepherd dogs were used for this study. after standardized trauma to the subglottic area, the dogs were divided into three groups. group a received curcumin (450 mg/ day) for 15 days; group b received...

results compared to pre-op scores, pf, ss, and vas scores for back, buttock and leg pain had a significant mean decrease at 6, 12, 24 months post-op (p < 0.05). based on the zcq and vas scores, a success rate of 79% (27.34), 78% (30.38) and 74% (17.23) were achieved at six months, 12 months, and 24 months respectively. conclusions x-stop is a safe and effective treatment for nic that provides m...

myocardial fractional flow reserve (ffr) is a new index of the functional significance of intermediate coronary stenoses that is calculated from pressure measurements made during coronary arteriography. the aim of this study was to evaluate the correlation between non-hyperemic coronary pressure dicrotic notch and fractional flow reserve (ffr). a consecutive of 114 patients (73 men and 41 women...

BACKGROUND Estrogen receptor (ER)-mediated effects have been associated with the modulation of myocardial hypertrophy in animal models and in humans, but ER expression in the human heart and its relation to hypertrophy-mediated gene expression have not yet been analyzed. We therefore investigated sex- and disease-dependent alterations of myocardial ER expression in human aortic stenosis togethe...