Ion channels are membrane protein complexes mediating passive ion flux across the cell membranes. Every organism has a certain set of that define its physiology. Dinoflagellates ecologically important microorganisms characterized by effective physiological adaptability, which backs up their massive proliferations often result in harmful blooms (red tides). In this study, we used bioinformatics ...

The large conductance, calcium-activated (BK-type) potassium channels are regulators of voltage-dependent calcium entry in many cell types. The BK channel accessory β1 subunit promotes channel activation in smooth muscle and is required for proper tone in the vasculature and bladder. However, although BK channels have also been implicated in airway smooth muscle function, their regulation by th...

An important event during apoptosis is regulated cell condensation known as apoptotic volume decrease (AVD). Ion channels have emerged as essential regulators of this process mediating the release of K(+) and Cl(-), which together with osmotically obliged water, results in the condensation of cell volume. Using a Grade IV human glioblastoma cell line, we examined the contribution of calcium-act...