نتایج جستجو برای: dendritic structure

تعداد نتایج: 1615344  

Journal: :Science 1999
M Maletic-Savatic R Malinow K Svoboda

Activity shapes the structure of neurons and their circuits. Two-photon imaging of CA1 neurons expressing enhanced green fluorescent protein in developing hippocampal slices from rat brains was used to characterize dendritic morphogenesis in response to synaptic activity. High-frequency focal synaptic stimulation induced a period (longer than 30 minutes) of enhanced growth of small filopodia-li...

Journal: :Journal of leukocyte biology 1999
S Gardella C Andrei S Costigliolo A Poggi M R Zocchi A Rubartelli

We show that interleukin-18 is constitutively produced by dendritic cells; synthesis and secretion are poorly affected by maturative stimuli. Challenge of dendritic cells with autologous anti-tetanus toxoid T lymphocytes results in a secretory switch, with induction of secretion of biologically active interleukin-18 and decrease of its intracellular content. Similarly, when dendritic cells are ...

2007
David Mould Jeremy Long

Dendritic or branching structures are commonly seen in natural phenomena such as lightning, cracking and vegetal growth. They are also often used for artistic or decorative purposes. We present a new method for modeling dendritic structures based on a path planning approach. Our method includes the use of a partial nonscalar distance metric that gives us effective and flexible control handles o...

Background: Alginate materials have been widely employed for biomedical applications ranging from wound healing to cancer treatment. However, how alginate materials affect the immune system is largely unknown. Objective: To explore the impact of alginate materials on immune system. Methods: The effect of three types of alginate materials, low viscosity, high viscosity and particulate alginate, ...

2004
Serkan Oray Earl Miller Mark Bear Yasunori Hayashi Takao Hensch Ania Majewska

This thesis takes as its subject three model systems which exhibit interesting properties in the developing nervous system. The first study details the developmental properties of dendritic spines, the principle sites of excitatory synaptic contacts, during a period of synaptogenesis in the developing mouse cortex. The second study extends these findings and examines the properties of dendritic...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
Mariko Kato Hayashi Heather M Ames Yasunori Hayashi

Homer is a crucial postsynaptic scaffolding protein involved in both maintenance and activity-induced plasticity of the synapse. However, its quaternary structure has yet to be determined. We conducted a series of biophysical experiments that provide the first evidence that Homer forms a tetramer via its coiled-coil domain, in which all subunits are aligned in parallel orientation. To test the ...

2014
Pooja Arora Andres Baena Karl O.A. Yu Neeraj K. Saini Shalu S. Kharkwal Michael F. Goldberg Shajo Kunnath-Velayudhan Leandro J. Carreño Manjunatha M. Venkataswamy John Kim Eszter Lazar-Molnar Gregoire Lauvau Young-tae Chang Zheng Liu Robert Bittman Aymen Al-Shamkhani Liam R. Cox Peter J. Jervis Natacha Veerapen Gurdyal S. Besra Steven A. Porcelli

Many hematopoietic cell types express CD1d and are capable of presenting glycolipid antigens to invariant natural killer T cells (iNKT cells). However, the question of which cells are the principal presenters of glycolipid antigens in vivo remains controversial, and it has been suggested that this might vary depending on the structure of a particular glycolipid antigen. Here we have shown that ...

Journal: :Journal of neurophysiology 2001
G Svirskis A Gutman J Hounsgaard

Understanding how voltage-regulated channels and synaptic membrane conductances contribute to response properties of neurons requires reliable knowledge of the electrotonic structure of dendritic trees. A novel method based on weak DC field stimulation and the classical method based on current injection were used to obtain two independent estimates of the electrotonic structure of motoneurons i...

2015
Rujia Zou Zhenyu Zhang Muk Fung Yuen Junqing Hu Chun-Sing Lee Wenjun Zhang

Herein, we designed and synthesized for the first time a series of 3D dendritic heterojunction arrays on Ni foam substrates, with NiCo2S4 nanowires as cores and NiCo2O4, NiO, Co3O4, and MnO2 nanowires as branches, and studied systematically their electrochemical performance in comparison with their counterparts in core/shell structure. Attributed to the following reasons: (1) both core and bran...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1982
P K Rose

The branching structure of the stem dendrites of five motoneurons innervating the dorsal neck muscles, biventer cervicis and complexus, was examined in the adult cat using intracellular staining techniques. The dendritic tree of each motoneuron was reconstructed completely and then dissected into several parts, each corresponding to the branches. Twenty-five of the 49 stem dendrites examined ha...

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