BACKGROUND 16S ribosomal DNA (rDNA) amplicon sequencing is frequently used to analyse the structure of bacterial communities from oceans to the human microbiota. However, computational power is still a major bottleneck in the analysis of continuously enlarging metagenomic data sets. Analysis is further complicated by the technical complexity of current bioinformatics tools. RESULTS Here we pr...

Telecommunication wavelength division multiplexing systems (WDM) demand high fiber-to-fiber coupling to minimize signal loss and maximize performance. WDM systems, with increasing data rates and narrow channel spacing, must maintain performance over the designated wavelength band and across a wide temperature range. Traditional athermal optical design techniques are coupled with detailed thermo...

Relay-Based Circuits In article number 2200584, Dinesh Pamunuwa and co-workers report the first in-plane, single-contact 4-terminal relay a 1-to-2 demultiplexer built from only two relays compared to ten conventional 3-terminal relays. The technique of body biasing reduce pull-in voltage is also demonstrated, which has potential for major power savings as consumption varies quadratically with v...