Delirium occurs as a pathophysiological state in connection with various diseases, particularly among patients in critical care. Since it may be a life-threatening condition, any physician should be able to initiate correct assessment and treatment of delirium. This review summarizes current knowledge on care of patients with delirium. The symptoms of delirium contain primarily disturbance of c...

BACKGROUND Delirium is the most frequent complication among older people following hospitalisation. Delirium may be prevented in about one-third of patients using a multicomponent intervention. However, in the United Kingdom, the National Health Service has no routine delirium prevention care systems. We have developed the Prevention of Delirium Programme, a multicomponent delirium prevention i...

Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery from delirium. Participants were assessed twice weekly using MoCA, DRS-R98, and APACHE II scales. BDNF levels were estimated using an ELISA method. Delirium was defined with DRS-...

BACKGROUND Delirium after surgery is a common condition that leads to poor outcomes. Few studies have examined the effect of postoperative delirium on outcomes after cardiac surgery. OBJECTIVES To assess the relationship between delirium after cardiac surgery and the following outcomes: length of stay after surgery, prevalence of falls, discharge to a nursing facility, discharge to home with ...

OBJECTIVE Delirium is a highly prevalent and deleterious disorder in terminally ill cancer patients. We assessed whether a multicomponent preventive intervention was effective in decreasing delirium incidence and severity among cancer patients receiving end-of-life care. METHODS A cohort of 1516 patients was followed from admission to death at seven Canadian palliative care centers. In two of...

BACKGROUND Current literature does not identify the significance of underlying cognitive impairment and delirium in older adults during and 30 days following acute care hospitalization. OBJECTIVE Describe the incidence, risk factors, and outcomes associated with incident delirium superimposed on dementia. DESIGN A 24-month prospective cohort study. SETTING Community hospital. PATIENTS A...

This article reviews the incidence, pathophysiological hypotheses, and etiology of postoperative delirium, especially in the elderly. Preoperative, intraoperative, and postoperative risk factors for delirium following surgery are discussed. Results of various studies on postoperative delirium appear hardly comparable due to methodological and population differences. Therefore, it is difficult t...

OBJECTIVE To describe a single-institution pilot study regarding prevalence and risk factors for delirium in critically ill children. DESIGN A prospective observational study, with secondary analysis of data collected during the validation of a pediatric delirium screening tool, the Cornell Assessment of Pediatric Delirium. SETTING This study took place in the PICU at an urban academic medi...

results trail making test part b cognitive test showed statistically significant in comparison for pre and post exposure of anesthetics. this difference was seen in the desflurane group. other cognitive tests did not show differences on exposure to the anesthetic gases. conclusions this study questioned the difference between volatile anesthetic agent’s effects on patients completing a battery ...

BACKGROUND Postoperative delirium can result in increased postoperative morbidity and mortality, major demand for postoperative care and higher hospital costs. Hypnotics serve to induce and maintain anaesthesia and to abolish patients' consciousness. Their persisting clinical action can delay postoperative cognitive recovery and favour postoperative delirium. Some evidence suggests that these u...