The membrane attack complex (MAC) of the complement system induces a necrotic-type cell death. Earlier findings suggested that Bcl-2 protects cells from MAC-induced necrosis. Here we examined the involvement of Bid, a proapoptotic protein, in MAC-induced cytotoxicity. Bid knockout (Bid-/-) mouse embryonic fibroblasts (MEF) and primary fibroblasts were damaged by complement but to a significantl...

Article history: Received 19 August 2014 Received in revised form 19 September 2014 Accepted 29 September 2014 Available online 3 November 2014

This paper considers the sealed bid and ascending auction, which both identifies the minimum Walrasian equilibrium prices and where truthful preference revelation constitutes an equilibrium. Even though these auction formats share many theoretical properties, there are behavioral aspects that are not easily captured. To explore this issue in more detail, this paper experimentally investigates w...

The Oligocene-Miocene granitic rocks of Deh Siahan, part of central Iranian volcanic belt, are intruded into Eocene volcano-sedimentary complex where their contact is marked by albite-epidote hornblende hornfels facies and granitic apophyses. The granitic rocks show enhanced LIL element abundances and low HFS/LIL ratios. Geochemical data, various trace element discriminant diagrams, enhanced Y/...

O labor markets are Web-based platforms that enable buyers to identify and contract for information technology (IT) services with service providers using buyer-determined (BD) auctions. BD auctions in online labor markets either follow an open or a sealed bid format. We compare open and sealed bid auctions in online labor markets to identify which format is superior in terms of obtaining more b...