نتایج جستجو برای: deguelin

تعداد نتایج: 136  

2015
Saurabh Bundela Anjana Sharma Prakash S. Bisen Arianna L. Kim

Oral cancer is one of the main causes of cancer-related deaths in South-Asian countries. There are very limited treatment options available for oral cancer. Research endeavors focused on discovery and development of novel therapies for oral cancer, is necessary to control the ever rising oral cancer related mortalities. We mined the large pool of compounds from the publicly available compound d...

Journal: :Biology of reproduction 2007
Yan Li Vashe Chandrakanthan Margot L Day Chris O'Neill

Paf (1-o-alkyl-2-acetyl-sn-gylcero-3-phosphocholine) is a putative autocrine survival factor for the preimplantation embryo. It acts to induce receptor-mediated calcium transients in the early embryo. Inhibitors of 1-o-phosphatidylinositol-3-kinase (PI3kinase), such as wortmannin and LY 294002, blocked these calcium transients, implicating the generation of phosphatidylinositol (3,4,5)-trisphos...

2016
Haruhiko Tokuda Gen Kuroyanagi Masanori Tsujimoto Rie Matsushima-Nishiwaki Shigeru Akamatsu Yukiko Enomoto Hiroki Iida Takanobu Otsuka Shinji Ogura Toru Iwama Kumi Kojima Osamu Kozawa

It is generally known that heat shock protein 27 (HSP27) is phosphorylated through p38 mitogen-activated protein (MAP) kinase. We have previously reported that HSP27 is released from human platelets associated with collagen-induced phosphorylation. In the present study, we conducted an investigation into the effect of thrombin receptor-activating protein (TRAP) on the release of HSP27 in platel...

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