background: hepatitis e virus (hev) infection is a self-limiting viral infection that can lead to severe complications and death. in different regions the epidemiology of this infection varies. in this study we evaluated the seroepidemiology of hepatitis e infection in jahrom, a city in southern iran. methods: this was a cross-sectional descriptive study of serum samples from 477 subjects, incl...

1. Premature delivery of foetal rats by uterine section results in the rapid appearance of tyrosine aminotransferase activity in foetal liver, after an initial lag period of 3-6hr. 2. The premature induction of activity is completely repressible by actinomycin D given soon after delivery and partially repressible by puromycin and amino acid analogues. 3. Glucagon injections into foetal rats in ...

A transaminase (aminotransferase, EC 2.6.1) fraction was partially purified from shoot tips of pea (Pisum sativum L. cv. Alaska) seedlings. With alpha-ketoglutarate as co-substrate, the enzyme transaminated the following aromatic amino acids: d,l-tryptophan, d,l-tyrosine, and d,l-phenylalanine, as well as the following aliphatic amino acids: d,l-alanine, d,l-methionine, and d,l-leucine. Of othe...

The aim of the present work was to develop a biochemical, histologic and immunohistochemical study about the potential hepatotoxic effect of d-limonene - a component of volatile oils extracted from citrus plants. Blood alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) from d-limonene-treated animals were determined and compared to morphologic hepati...

D-Amino acid aminotransferase, purified to homogeneity and crystallized from Bacillus sphaericus, has a molecular weight of about 60,000 and consists of two subunits identical in molecular weight (30,000). The enzyme exhibits absorption maxima at 280, 330, and 415 nm, which are independent of the pH (5.5 to 10.0), and contains 2 mol of pyridoxal 5'-phosphate per mol of enzyme. One of the pyrido...

2108 CLINICAL CHEMISTRY, Vol. 32, No. 11, 1986 References 1. Jung K, Mildner D, Jacob B, et al. On the pyridoxal 5’-phosphate stimulation of aspartate aminotransferase and alanine aminotransferase in serum and erythrocytes of patients undergoing haemodialysis and with kidney transplants. Clin Chim Acts 1981;115:10510. 2. Oimomi M, Ishikana K, Kawasaki 1, et al. Plasma carbamylated protein in re...

To evaluate the protective activity of fruits against liver injury, 22 different fruits were fed to rats with liver damage caused by D-galactosamine, a powerful liver toxin. As measured by changes in the levels of plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST), avocado showed extraordinarily potent liver injury suppressing activity. Five active compounds were isolate...

Table. Laboratory Data Leukocytes (× 10 6.2 Neutrophils (× 10 4.5 Eosinophils (× 10 0.1 Basophils (× 10 0 Monocytes (× 10 0.7 Lymphocytes (× 10 1 Hemoglobin (g/dL 6.9 Platelets (× 10 21.8 CRP (mg/dL 5.52 ESR (mm/h >150 BUN (mg/dL 19 Creatinine (mg/d 0.89 AST (mU/m 10 ALT (mU/m 3 LDH (mU/ 112 Antinuclear antibody (Anti-CCP antibody (Rheumatoid factor (CRP: C-reactive protein, ESR: erythrocyte se...

To evaluate the protective effects of fruit juices against D-galactosamine (GalN)-induced liver injury, lyophilized fruit juices (total 12 kinds) were fed to rats for 7 d, and then we evoked liver injury by injecting GalN. The juice of camu-camu (Myrciaria dubia) significantly suppressed GalN-induced liver injury when the magnitude of liver injury was assessed by plasma alanine aminotransferase...

Background: SEN virus (SENV) is the latest virus proposed as a cause of unknown hepatitis cases. Among nine detected genotypes of the virus, genotypes D and H are more frequent in hepatitis cases of unknown origin. The aim of this study was to determine the frequency of SENV-D and SENV-H genotypes in the sera of healthy individuals and hepatitis B and C patients. Methods: Totally, 200 serum sam...