Glucosamine (2-amino-2-deoxy-d-glucose) and glucosamine-containing products have been reported to have efficacy in the treatment of various musculoskeletal disorders. Glucosamine's efficacy, including reduction of pain, is attributed to disease-modifying properties, specifically to cartilage-rebuilding associated with modulation of interleukin-1-induced activation of chondrocytes and to inhibit...

We examined the effects of oral glucosamine hydrochloride (GlcN), N-acetyl-D-glucosamine (GlcNAc) and d-glucose (Glc) administration on plasma total free amino acid (PFAA) concentrations in dogs. The PFAA concentrations increased in the control group and the GlcNAc group at one hour after feeding, and each amino acid concentration increased. On the other hand, in the GlcN group and the Glc grou...

Hen egg white lysozyme, fully inactivated by the affinitylabeling reagent, the 2’,3’-epoxypropyl fl-glycoside of di-(NaCetyl-D-glUCOSamine), contained 1 mole of the label per mole of protein. Total enzymatic digestion of the reduced and carboxymethylated affinity-labeled enzyme afforded, as a major radioactive product, a compound composed solely of aspartic acid and glucosamine at the molar rat...

Chitosan, a copolymer of glucosamine and N-acetyl glucosamine, is a polycationic, biocompatible and biodegradable polymer. In addition, chitosan has different functional groups that can be modified with a wide array of ligands. Because of its unique physicochemical properties, chitosan has great potential in a range of biomedical applications, including tissue engineering, non-viral gene delive...

objective(s): the aim of this study was to synthesis new dental nanocomposites reinforced with fabricated glass nanoparticles and compare two methods for fabrication and investigate the effect of this filler on mechanical properties. materials and methods: the glass nanoparticles were produced by wet milling process. the particle size and shape was achieved using psa and sem. glass nanoparticle...

background: use of glucosamine as an alternative treatment for osteoarthritis is becoming more frequent, including in those who have diabetes at the same time. the results from in vitro and animal studies propose that glucosamine may inversely affect glucose metabolism. however, the recommended dose of oral glucosamine in healthy people or diabetics did not have such effects consistently. the a...

Influenza-virus-infected cells were labelled with radioactive sugars and extracted to give fractions containing lipid-linked oligosaccharides and glycoproteins. The oligosaccharides linked to lipid were of the 'high-mannose' type and contained glucose. In the glycoprotein fraction, radioactivity was associated with virus proteins and found to occur predominantly in the 'high-mannose' type of gl...

A diastereoselective domino nitro-Michael/Henry reaction involving a beta-hydroxyaldehyde and a nitroalkene provides direct access to fully functionalized D-glucosamine monosaccharides.

Rats fed a purified diet containing 1% erotic acid for 2 days accumulate large amounts of uridine diphospho-Nacetylhexosamine in the liver. This accumulation is not the result of a block in utilization of uridine diphospho-Nacetylhexosamine, but probably results from increased synthesis de novo. These rats appear to suffer from a defect in the feedback control of L-glutamine-D-fructose 6-phosph...