نتایج جستجو برای: d amino acids

تعداد نتایج: 886824  

2017
Michael Garton Maryam Sayadi Philip M Kim

Redesigning protein surface topology to improve target binding holds great promise in the search for highly selective therapeutics. While significant binding improvements can be achieved using natural amino acids, the introduction of non-canonical residues vastly increases sequence space and thus the chance to significantly out-compete native partners. The potency of protein inhibitors can be f...

Journal: :Journal of Biological Chemistry 1951

Journal: :iranian journal of pharmaceutical research 0
akbar mobinikhaledi department of chemistry, faculty of science, arak university, arak 38156-8-8349, iran behvar asghari department of plant production and breeding engineering, faculty of engineering and technology, imam khomeini international university, qazvin, iran mahsa jabbarpour department of chemistry, faculty of science, arak university, arak 38156-8-8349, iran.

in an endeavor to find a novel series of antihyperglycemic agents, new benzimidazole and pyrimidine derivatives were successfully synthesized efficiently in high yield with high purity, starting from amino acids in the presence of phosphorus oxychloride (pocl3). the synthesized compounds were identified by 1h-nmr, 13c-nmr, ft-ir spectroscopic techniques and elemental analysis. all products were...

Journal: :iranian journal of applied animal science 2015
a.f. agboola e.a. iyayi

an experiment was conducted to determine apparent ileal digestibility of crude protein (cp) and amino acids (aa) and digestible cp and aa of fish meal (fm) in 21-d-old broiler chickens using the regression technique. four diets containing 0, 1, 2, and 3% fm in place of cornstarch were formulated with fm as the sole contributor of cp and aas in the sequential diets. eighty 14-d-old broiler chick...

Journal: :پژوهش های علوم و صنایع غذایی ایران 0
(pages 87-98) m.r. ovissipour a. abedian kenari a. motamedzadegan r. m. nazari

in current study, protein hydrolysates were produced using microbial proteases of alcalase, protamex and flavourzyme from yellowfin tuna viscera. the results indicated that, protein hydrolysate from alcalase, had significantly higher protein content, nitrogen recovery and degree of hydrolysis than the others (p 0.05). the results of amino acids composition revealed that all hydrolysates were al...

Journal: :The Journal of clinical investigation 1987
K Lundholm K Bennegård H Zachrisson F Lundgren E Edén A C Möller-Loswick

Flux rates of amino acids were measured across the leg after an overnight fast in resting human volunteers. A balanced amino acid solution was, after a primed infusion, continuously infused for 2 h at each of three step-wise and increasing rates corresponding to 8.3, 16.7, 33.2 mg N/kg per h that were equivalent to 0.2, 0.4, 0.8 g N/kg per d. Flux of amino acids across the leg was compared with...

Journal: :Circulation 2002
Mohamad Navab G M Anantharamaiah Susan Hama David W Garber Manjula Chaddha Greg Hough Roger Lallone Alan M Fogelman

When apolipoprotein A-I mimetic peptides synthesized from either D- or L-amino acids were given orally to LDL receptor-null mice, only the peptide synthesized from D-amino acids was stable in the circulation and enhanced the ability of HDL to protect LDL against oxidation. The peptide synthesized from L-amino acids was rapidly degraded and excreted in the urine. When a peptide synthesized from ...

Keyvan Sadri, Mohammad Hossein Babaei Mostafa Gandomkar Reza Najafi Seyed Esmaeil Sadat Ebrahimi Seyed Rasoul Zakavi,

  Introduction: Radioimmunotherapy (RIT) is a very promising new therapy for the treatment of recurrent B-Cell non-Hodgkin's lymphoma (NHL). Iodine-131 is the most frequently used nuclide in clinical RIT, but its usefulness has been limited by dehalogenation of monoclonal antibodies labeled via conventional methods. To circumvent this problem, we have synthesized a tr...

Journal: :Journal of the American Chemical Society 2007
Hyunjung Park Kwan Mook Kim Areum Lee Sihyun Ham Wonwoo Nam Jik Chin

L-Amino acids dominate the natural world almost to the exclusion of D-amino acids. However, some important D-amino acids1 have been found in biology, notably as neurotransmitters (D-serine)2 and as building blocks (D-alanine) for bacterial cell wall synthesis.3 There has been considerable interest in understanding the mechanism of the so-called “L to D conversion” of amino acids4 since enzymes ...

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