to review the diffrent aspects of gender, subtype of cah, management and results in all our patients with ambiguous genitalia diagnosed as congenital adrenal hyperplasia during the past 30 years. methods: the files of all our patients with cah reviewed retrospectively. results: out of 256 patients who had ambiguous genitalia due to cah, 96% were female and 4% were male. 21-ohd was diagnosed in ...

tumors of t h e male u ret h ra are r a re, co m prising <1% of urolo g ic malignancies. this is a re po rt of a 44-ye a r-old man pre s ented with a 4 -month history of gross initi a l h e maturia and d y s u ri a . af t e r exami n ing the pa t ien t , we found a firm mass ex t ending 1 c m within the p roxim a l bulb a r uret h ra and a pathologic report of moderately differen t iated sq u a...

conclusions since the severity of the behavioral symptoms in the 6-ohda-induced model of parkinson disease reflects the degree of the lesion in substantia nigra (sn) dopaminergic neurons, it is suggested that using the combination had neuroprotective effects. the obtained data suggest a synergistic neuroprotective and antiparkinsonian effect for flu, glib and b com. at least, a part of this eff...

background: meict is the first chlorotoxin-like peptide isolated from the iranian scorpion mesobuthus eupeus. chlorotoxin (ctx) is a neurotoxin that specially binds to (mmp-2) on ma-lignant cells and now is used in treatment of glioma. in the present study, we have used homology modeling to propose the 3d structure of meictand analyze its interaction with mmp-2 and its snp types. methods:the st...

background cancer is one of the most significant causes of death around the world, and oral squamous cell carcinoma (oscc) represents 90% of oral malignancies. ferula persica has been used for treatment of different diseases in iranian traditional medicine. previous studies reveal some evidence relating to the value of preventing malignancies through f. persica. objectives the aim of the presen...

urinary 1-hydroxypuren (1-ohp) is commonly used as a major metabolite and biological indicator of the overall exposure to polycyclic aromatic hydrocarbons (pahs). for evaluation of human exposure to such compounds, biological monitoring is an essential process, in which, preparation of samples is one of the most time-consuming and error-prone aspects prior to chromatographic techniques. in this...

background: hepatic ischemia/reperfusion injury (i/ri) is a multifactorial pathophysiologic process which can lead to liver damage and dysfunction. this study examined the protective effect of dexamethasone on the gene expression of endothelial nitric oxide synthase (enos) and endothelin-1 (et-1) and on the liver tissue damage during warm hepatic i/r. methods: a total of 32 male wistar rats was...

recovery of metabolites from fermentation broth by solvent extraction can be used to optimize fermentation processes. end-product reutilization, low product concentration and large volumes of fermentation broth and the requirements for large bioreactors, in addition to the high cost largely contributed to the decline in fermentative 2,3-butanediol production. extraction can successfully be used...

background: the aim of the present study was to investigate the immunomodulation effects of aqueous garlic extract (age) in the cultured macrophages infected by leishmania major . methods: after j774 macrophages proliferation in rpmi1640 and incubation with leishmania for 72 hours, age was added in doses of 9.25, 18.5, 37, 74 and 148 mg/ml for 18, 24 and 48 hours and cell culture supernatants w...