Secretory carcinoma (SC) is a rare recently described entity that has characteristics similar to those of secretory breast carcinoma. We report case 23 years old male with swelling on the parotid gland. The ultrasonography guided fine needle aspiration cytology was performed mass. Cytologically, background aspirate composed inflammatory cells admixed mucinous material. There were isolated as mu...

cellular and molecular pathways link thrombosis and innate immune system during sepsis. extrinsic pathway activation of protease thrombin through fviia and tissue factor (tf) in sepsis help activate its endothelial cell (ec) membrane protease activated receptor 1 (par-1). thrombin adjusts the ec cycle through activation of g proteins (g12/13), and later through rho gefs (guanine nucleotide exch...

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to recognition of abnormal cytoplasm and stimulator interferon genes (STING) signaling pathway. cGAS could mediate expression interferon-related genes, inflammatory-related factors, downstream chemokines, thus initiating immune response. The STING protein is key effector It widely expressed across cell types such as ...