We report the development of a simple and rapid PCR assay for quantitation of the cytomegalovirus (CMV) DNA load in polymorphonuclear leukocytes. Using this system, a very good correlation was found between a high number of CMV copies in the blood and the presence of CMV disease in subjects with AIDS.

Over the last decade, cytomegalovirus (CMV) has been suggested to promote the development of glioblastoma multiforme (GBM). Recent evidence demonstrates that CMV contributes to the progression of GBM in the context of oncosuppressor gene mutations. This finding provides further insights into the mechanisms whereby CMV exacerbates the malignancy of GBM.

Objective: Cytomegalovirus (CMV) is a well-known virus with major consequences in growing fetus, premature infants, and immune deficient individuals. There are few reports in prevalence of CMV infection in Iran, mainly in pregnant women. We conducted an epidemiological study to investigate the age-stratified seroprevalence and epidemiological characteristics of CMV infection in total inhabitant...

Necrotizing enterocolitis is a gastrointestinal emergency typical of premature infants. Intestinal strictures infrequently complicate medical or surgical treatment of necrotizing enterocolitis. Postnatal cytomegalovirus infection with gastrointestinal linvolvement has occasionally been described in subjects with necrotizing enterocolitis. We report the case of a full term infant presenting necr...

To evaluate the correlation of cytomegalovirus (CMV) and coronary artery disease (CAD), one-hundred patients with CAD and the same number of healthy individuals as a control group were randomly selected and studied for anti-CMV using ELISA method. Ninety percent of patients and 77 percent of the control group were anti-CMV positive and statistical analysis showed a significant correlation ...

Cytomegalovirus (CMV) is the leading cause of viral-associated congenital infections. Moreover, it can also be acquired. Between 50 to 80 percent world’s population seropositive for CMV and most clinical disease occurs in individuals previously infected with CMV. Rarely, serious infection has occurred healthy immune system. In contrast immunocompetent patients, higher morbidity mortality end or...

BACKGROUND Elevated levels of antibodies to Cytomegalovirus (CMV) have been associated with cognitive impairment, but the quantitative relationship between CMV antibody levels and domains of cognitive functioning in younger adults has not been established. METHODS We measured IgG class antibodies to Cytomegalovirus in 521 individuals, mean age 32.8 years. Participants were selected for the ab...

INTRODUCTION Although urine is considered the gold-standard material for the detection of congenital cytomegalovirus (CMV) infection, it can be difficult to obtain in newborns. The aim of this study was to compare the efficiency of detection of congenital CMV infection in saliva and urine samples. METHODS One thousand newborns were included in the study. Congenital cytomegalovirus deoxyribonu...

Cytomegalovirus colitis is uncommon in immunocompetent hosts. Thus, a case of bloody diarrhoea and weight loss in an immunocompetent elderly man is reported. Cytomegalovirus colitis was diagnosed by identifying inclusion bodies with positive immunohistochemistry for cytomegalovirus in the histological specimens obtained by colonoscopy. The patient responded to gancyclovir treatment. We conclude...

CYTOMEGALOVIRUS (CMV) disease results from a complex interplay among a variety of factors. the consequences of which are differences in the incidence and severity of CMV disease across different transplant populations. '-3 In May 1990. the small bowel transplantation (Sax) program was initiated at our institution. In this study we analyze the incidence and timing of CMV disease after sax and we...