Modern hormone replacement therapy (HRT) regimens contain oestrogen and progestogen, given either in a cyclical or continuous combined manner. Most endometrial biopsies from women on sequential HRT show weak secretory features. Approximately 15% show proliferative activity, although this figure may be less if more than nine days of progestogen is given in each cycle. A small proportion will sho...

OBJECTIVE Aberrant expression of the cell surface proteoglycan, syndecan-1, is found in many malignancies. The current study describes the immunohistochemical study of syndecan-1 expression in normal, hyperplastic, and malignant endometrial tissues for evaluation of application as a parameter of cancer progression in patients with endometrial hyperplasia. METHODS Immunohistochemical staining ...

UNLABELLED Parathyroid hormone-related peptide (PTH-rp) is a peptide initially purified from tumors with hypercalcemia, which is also produced in human endometrium. The aim of this study was to determine the frequency and tissue distribution of PTH-rp in normal, hyperplastic and malignant endometrium. MATERIALS AND METHODS Paraffin-fixed endometrial tissue was obtained randomly from women in ...

BACKGROUND Endometrial assessment by means of biopsy or sampling of endometrial cells is a minimally invasive alternative for dilatation and curettage (D&C) or hysteroscopy. The use of this technique is believed to reduce the cost of the diagnostic work-up for abnormal uterine bleeding without reducing accuracy. Because the authors were not aware of any systematic review of this test, they perf...

Diagnostic tools for common uterine disorders like cystic endometrial hyperplasia (CEH), mucometra, hydrometra or pyometra as well as effective treatments are discussed. Cystic Endometrial Hyperplasia (CEH), a chronical degenerative disease of the endometrium, coincedes with delayed uterine clearance of fluids after mating and reduced uterine contractions and perfusion. Since in bitches with CE...

BACKGROUND/AIM Fractal dimension (FD) is widely used in medicine and biology as a tool for defining features of structure. This study aimed to compare pathological endometrium (simple-complex hyperplasia and endometrial carcinoma), as well as the endometrial changes, during the phases of the menstrual cycle. The main goal was the objective measurement of fractal dimension and to refrain from su...

Current guidelines suggest endometrial biopsy in women ³40 years old with abnormal uterine bleeding (AUB) as they are at greater risk of hyperplasia (EH) or cancer (EC). In under 40 old, there no clear recommendations regarding biopsy. This should be carefully considered younger due to the associated risks that may affect fertility. We aim study profile EH/EC our population, optimise these high...

Introduction: Abnormal uterine bleeding (AUB) is among the most complex gynecological problems, especially during the middle and old age. The aim of this study was to assess the pathological findings in endometrial curettage samples of abnormal uterine bleeding and the risk factors associated with them. Methods: In our cross-sectional study, we included all the referring women with AUB compl...

The aim of the present work was to investigate deleterious effects first dose medroxyprogesterone acetate (MPA) on female genital system cats. study conducted 315 cats different breeds who received their (75 mg) MPA as a contraceptive. Complete animal identification and stage estrus were documented at admission. Physical, radiographic ultrasonographic examinations done that expressed manifestat...

background: transvaginal ultrasound is one of the most common means to examine endometrial cavity lesions although its negative results are more valuable. saline sonohysterography can reduce the number of false negative rates of endometrial lesions diagnoses in tamoxifen consumers. the objective of this study was to determine the diagnostic values of saline infusion sonohysterography (sis) and ...