نتایج جستجو برای: cylindrocarpon destructans var crassum

تعداد نتایج: 26187  

2017
Christina M Davy Michael E Donaldson Craig K R Willis Barry J Saville Liam P McGuire Heather Mayberry Alana Wilcox Gudrun Wibbelt Vikram Misra Trent Bollinger Christopher J Kyle

Mitigation of emerging infectious diseases that threaten global biodiversity requires an understanding of critical host and pathogen responses to infection. For multihost pathogens where pathogen virulence or host susceptibility is variable, host-pathogen interactions in tolerant species may identify potential avenues for adaptive evolution in recently exposed, susceptible hosts. For example, t...

2011
Shih-Tseng Lin Shang-Kwei Wang Chang-Yih Duh

Chemical investigation of the Dongsha Atoll soft coral Lobophytum crassum has afforded four new cembranoids, crassumols A-C (1-3) and 13-acetoxysarcophytoxide (4). The structures of these isolated compounds were elucidated by extensive NMR and HRESIMS experiments. The cytotoxicity and anti-HCMV (Human cytomegalovirus) activities of 1-4 were evaluated in vitro. Compound 4 exhibited cytotoxicity ...

2012
Cheng-Hung Lee Chia-Ying Kao Shih-Yao Kao Chih-Han Chang Jui-Hsin Su Tsong-Long Hwang Yueh-Hsiung Kuo Zhi-Hong Wen Ping-Jyun Sung

A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutr...

Journal: :Mycologia 2013
Jeffrey M Lorch Daniel L Lindner Andrea Gargas Laura K Muller Andrew M Minnis David S Blehert

The recent emergence of white-nose syndrome (WNS), a fungal disease causing unprecedented mortality among hibernating bats of eastern North America, has revealed a knowledge gap regarding fungal communities associated with bats and their hibernacula. We used culture-based techniques to investigate the diversity of fungi in soil samples collected from 24 bat hibernacula in the eastern United Sta...

Journal: :Conservation biology : the journal of the Society for Conservation Biology 2011
Janet Foley Deana Clifford Kevin Castle Paul Cryan Richard S Ostfeld

White-nose syndrome (WNS) is a fatal disease of bats that hibernate. The etiologic agent of WNS is the fungus Geomyces destructans, which infects the skin and wing membranes. Over 1 million bats in six species in eastern North America have died from WNS since 2006, and as a result several species of bats may become endangered or extinct. Information is lacking on the pathogenesis of G. destruct...

2012
M. J. Souza T. Cairns J. Yarbrogh S. K. Cox

A terbinafine impregnated subcutaneous implant was evaluated to determine if drug was released into isotonic saline over the course of 6 months at two different temperatures, 37°C and 4°C. These temperatures were chosen to simulate the nonhibernating (37°C) and hibernating body (4°C) temperatures of little brown bats (Myotis lucifugus). Insectivorous bats of North America, including little brow...

2014
Jan Zukal Hana Bandouchova Tomas Bartonicka Hana Berkova Virgil Brack Jiri Brichta Matej Dolinay Kamil S. Jaron Veronika Kovacova Miroslav Kovarik Natália Martínková Karel Ondracek Zdenek Rehak Gregory G. Turner Jiri Pikula

Host traits and phylogeny can determine infection risk by driving pathogen transmission and its ability to infect new hosts. Predicting such risks is critical when designing disease mitigation strategies, and especially as regards wildlife, where intensive management is often advocated or prevented by economic and/or practical reasons. We investigated Pseudogymnoascus [Geomyces] destructans inf...

Journal: :Medical Mycology Case Reports 2013

Journal: :Horticulturae 2023

During the summer of 2016, severe dieback was observed on young potted Prunus lusitanica (Portugal laurel) plants in a nursery Pistoia province (Tuscany, Italy). Cylindrocarpon-like isolates were consistently recovered from diseased plant tissues. The combination morphological and molecular traits, including sequence data histone 3 β-tubulin genes (HIS3, TUB2) internal transcribed spacers (ITS)...

2011
Nai-Lun Lee Jui-Hsin Su

Three new cembranoids, culobophylins A-C (1-3), along with two known compounds (4 and 5) were isolated from the cultured soft coral Lobophytum crassum. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. Among these metabolites, 2 is rarely found in cembranoids possessing an isopropyl moiety wit...

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