We report a microfabricated mechanical testing platform with on-chip strain sensors for in situ mechanical characterization of arrayed materials. The device is based on deformable elastomeric membranes that are actuated by pressure that is delivered through an underlying channel network. The bulging membranes compress material samples that are confined between the membranes and a rigid top-plat...

nowadays acoustic emission (ae) testing based on the kaiser effect (ke) is increasingly used to estimate the in-situ stress in laboratories. in this work, this effect is assessed on cylindrical specimens in numerical simulations of the cyclic loadings including loading, unloading, and re-loading cycles using a 3d code called the particle flow code (pfc) based upon the distinct element method. t...

192 LLE Review, Volume 68 A principal component of smoothing by spectral dispersion (SSD) is an electro-optic phase modulator that produces a cyclic wavelength modulation on nanosecond laser pulses. This article addresses the theory, design, manufacture, testing, and implementation of microwave phase modulators operating in the gigahertz-frequency range with particular application to both onean...

One function of airway epithelium is the secretion of mucins, which comprise an important component of the mucous lining layer. We demonstrate that rabbit tracheal epithelial cells grown in primary culture incorporate [3H]glucosamine into material released into the medium which is characterized as mucin by the following criteria: high Mr, monosaccharide composition, ion-exchange behaviour diffe...

Preparation of several novel potassium salts of 4-substituted aminoazobenzenesulfonic acids by the simple and convenient reaction of insoluble 4-sulfobenzenediazonium chloride with some (hetero)cyclic amines of various ring sizes is reported. The compounds obtained have shown potential antiinflammatory activity in biological testing.

Daptomycin, a new cyclic lipopeptide, was recently approved for the treatment of infections by gram-positive organisms, including infections with methicillin-resistant Staphylococcus aureus (MRSA). A patient infected with infected with MRSA developed resistance to daptomycin after prolonged exposure, which resulted in clinical failure. Clinicians should be aware of the possibility of daptomycin...

BACKGROUND The development of a gonorrhea vaccine is challenged by the lack of correlates of protection. The antigenically variable neisserial opacity (Opa) proteins are expressed during infection and have a semivariable (SV) and highly conserved (4L) loop that could be targeted in a vaccine. Here we compared antibodies to linear (Ab(linear)) and cyclic (Ab(cyclic)) peptides that correspond to ...

INTRODUCTION The aim of this study was to compare the cyclic fatigue resistances of nickel-titanium rotary glide path files, which are manufactured as single-file systems, under dynamic model. METHODS Twenty ProGlider (16.02) and 20 One G (14.03) nickel-titanium glide path files were included in this study. Cyclic fatigue tests were performed with specifically manufactured dynamic cyclic test...