This prospective controlled study recorded the anthropometric data and measured the circulating insulin-like growth factor-I (IGF-I) in 16 children with congenital cyanotic heart disease before and a year after surgical intervention. At presentation patients were significantly shorter [length SD scores (LSDS) = -2.44 +/- 1.31], vs. controls (LSDS = -0.25 +/- 0.18). After surgical treatment the ...

Background: Children with congenital heart disease (CHD) are prone to malnutrition and growth retardation. This study aimed to compare growth status between children with CHD and healthy children.                Materials and Methods: This case–control study included 310 children with CHD and 300 healthy children matched in age and gender. CHD patients grouped according to cardiac diagnosis: ...

congenital heart disease. Circulation 1993;87:1954–1959. 23. Ammash N, Warnes CA. Cerebrovascular events in adult patients with cyanotic congenital heart disease. J Am Coll Cardiol 1996;28:768–772. 24. Groenink M, Lohuis TAJ, Tijssen JPG, Naeff MSJ, Hennekam RCM, van der Wall EE, Mulder BJM. Survival and complication free survival in Marfan’s syndrome: implications of current guidelines. Heart ...

OBJECTIVE Ambient hypoxia impairs the airway epithelial Na transport, which is crucial in lung edema reabsorption. Whether chronic systemic hypoxemia affects airway Na transport has remained largely unknown. We have therefore investigated whether chronic systemic hypoxemia in children with congenital heart defect affects airway epithelial Na transport, Na transporter-gene expression, and short-...