BACKGROUND AND AIMS Oral lichen planus is a relatively common chronic oral mucosal disease of unknown etiology. Regarding numerous studies on the immunologic factors involved in the etiology of lichen planus, the present study evaluated the serum interleukin-17 (IL-17) level in patients with erosive and non-erosive oral lichen planus. MATERIALS AND METHODS This descriptive analytical study in...

oral lichen planus is diagnosed according to clinical and histopathological characteristics.some times all of the classical  histopathological features can not be seen.in some articles the presence of mast cells have been noted below the epithelium of oral lichen planus patients.the following study was done to evaluate the number of mast cells in the histopathological sections of 20 oral lichen...

background and aims. oral lichen planus is a common chronic inflammatory disease of the oral mucosa with malignant potential, pathogenesis of which is not still well known. free radicals and reactive oxygen species can play an important role in the pathogenesis of oral lichen planus. the aim of this study was to investigate salivary oxidative stress and antioxidant systems in patients with oral...

Lichen sclerosus, lichen planus, and lichen simplex chronicus are three of the most common non-neoplastic epithelial disorders of the vulva. Lichen sclerosus is characterized by intense vulvar itching and can affect men and women of all ages, but it manifests most commonly in postmenopausal women. Patients with lichen sclerosus have an increased risk of developing squamous cell carcinoma, and t...

iichen planus is a relatively common disease of unknown etiology that occurs on the skin and oral mucosa. Compared with skin lesions, the mucosal affections have a far more chronic nature and often persist for many years (1). Because of the morbidity associated with these oral lesions and their propensity for malignant development (2), oral lichen planus occupies an important place in dental pr...

Lichen sclerosus (LS) et atrophicus is a disease of unknown etiology, although hereditary, endocrine, and autoimmune factors are known to be involved. While the anal and genital regions are predominantly affected, only 2.5% of patients present with extragenital lesions, particularly of the trunk, neck, and upper limbs. The possible relationship between lichen sclerosus et atrophicus and both li...

Sir, Cutaneous drug reactions have a wide variety of clinical features. Lichenoid drug eruptions (LDE) are rare and it may be difficult to differentiate them from idiopathic lichen planus (1, 2). Gold, quinine, quinidine and penicillamine are well-known inducers of such eruptions (1, 2), but there are only a few reports of lichenoid eruption induced by 3-hydroxy-3-methyl-glutaryl coenzyme A (HM...

Lichen planus is an immunologically mediated mucocutaneous disease that triggered by varied etiological agents. The oral lichenoid reaction considered a variant of the needs to be clearly diagnosed as separate entity from lichen and treated. They follow strict cause-effector relationship, protocols suggest differentiation. has clinical forms in mucosa cutaneously different prognosis. This condi...

OBJECTIVE To assess the association of lichen planus with liver complaints and with known aetiological factors of liver diseases. DESIGN Multicentre case-control study. Interviews were conducted by trained medical investigators on the basis of a structured questionnaire. At the interview patients and controls were asked for consent to blood samples being taken to determine transaminase activi...