BACKGROUND Hookworm-related cutaneous larva migrans (HrCLM) is a neglected tropical skin disease associated with significant clinical pathology. Little knowledge exists about prevalence and risk factors of HrCLM in endemic regions. METHODOLOGY/ PRINCIPAL FINDINGS To understand the epidemiology of HrCLM in Amazonia, we conducted a cross-sectional study in a resource-poor township in Manaus, Br...

Human toxocariasis is a helminthozoonosis due to the migration of Toxocara species larvae through human organism. Humans become infected by ingesting either embryonated eggs from soil (geophagia, pica), dirty hands or raw vegetables, or larvae from undercooked giblets. The diagnosis relies upon sensitive immunological methods (ELISA or western-blot) which use Toxocara excretory-secretory antige...

Two brothers with visceral larva migrans caused by Trichuris vulpis were diagnosed after they had been investigated for an eosinophilia. Both patients were almost asymptomatic. The diagnosis of visceral larva migrans was based on the results of immunoelectrophoretic studies and no liver biopsy was performed. After administration of thiabendazole, the number of eosinophils and serum total IgE le...

To determine whether increased migration is associated with an increase in incidence of toxocariasis (visceral larva migrans), we analyzed clinical data obtained from immigrants from Latin America. Although infection with Toxocara sp. roundworm larvae is distributed worldwide, seroprevalence is highest in tropical and subtropical areas.

human visceral and ocular toxocariasis can occasionally be a serious or life-threatening condition, especially for children. the diagnosis and confirmation of the disease mostly based upon serological tests. the purpose of the present study was to evaluate somatic antigen with regard to its application in a routine diagnostic laboratory test. using gel-filtration chromatography, fraction no.1 o...

We present a case of visceral larva migrans which came as a complete histologic surprise. The patient was operated as a case of chronic cholecystitis and was found at operation to have multiple hepatic nodules. A cholecystectomy with a biopsy of the liver nodule was performed. Histopathologically a diagnosis of visceral larva migrans was made. To our knowledge this is the first case report of t...

There are many causes of persistent eosinophilia in children, but Perlingiero and Gyorgy (1947) described a case in which there was also hepatic enlargement, anaemia and fever. Two years later Zuelzer and Apt (1949) described eight similar cases and suggested that they formed a definite syndrome. Since then several more have been reported and it has been shown that this syndrome is frequently c...