Lacaziosis or Jorge Lobo's disease is a fungal, granulomatous, chronic infectious disease caused by Lacazia loboi, which usually affects the skin and subcutaneous tissue. It is characterized by slow evolution and a variety of cutaneous manifestations with the most common clinical expression being nodular keloid lesions that predominate in exposed areas. We report the case of a patient who had a...

BacillusCalmette-Guerin (BCG) vaccine, a live attenuated strain of Mycobacterium bovis was developed in 1908 and it was first used in 1921. Its safety profile is widely accepted globally, with just a few side effects including cutaneous inflammatory papules and granulomas which are common within the first few weeks after vaccination. A few reports of delayed BCG granulomas many years following ...

Introduction: Sarcoidosis is a systemic non-caseating granulomatous disorder of unknown etiology that may affect multiple organ systems. Head and neck involvement can present in unusual often nonspecific ways. Observations : We report three cases sarcoidosis with orofacial manifestations: one African American patient an existing diagnosis who presented perioral cutaneous by sarcoidosis, two Cau...

The recent identification of genetic mutations leading to dysfunction of inflammatory and apoptotic pathways, has allowed to characterise a group of diseases, recognised as monogenic autoinflammatory syndromes. Among those, Blau syndrome (BS) and early-onset sarcoidosis (EOS) have been identified as familial and sporadic phenotypes of the same non-caseating granulomatous form. Both the diseases...

Yau Ma Tei Dermatology Clinic, 12/F, Yau Ma Tei Specialist Clinic, 143 Battery Street, Kowloon, Hong Kong Rosai-Dorfman disease (RDD) is a benign idiopathic proliferative disorder. It commonly affects lymph nodes, but other organs can be involved. RDD limited to skin is rare. We report a 45-yearold Chinese man suffering from RDD. The first three skin biopsies revealed granulomatous inflammation...

1. Allo MD, Miller J, Townsend T, Tan C. Primary cutaneous aspergillosis associated with Hickman intravenous catheters. N Engl J Med 1987;317: 1105–8. 2. Walmsley S, Devi S, King S, Schneider R, Richardson S, Ford-Jones L. Invasive Aspergillus infections in a pediatric hospital: a ten-year review. Pediatr Infect Dis J 1993;12:673–82. 3. Segal BH, DeCarlo ES, Kwon-Chung KJ, Malech HL, Gallin JI,...

Margineda C.A., Odriozola E., Moreira A.R., Cantón G., Micheloud J.F., Gardey P., Spetter M. & Campero C.M. 2013. Atypical actinobacillosis in bulls in Argentina: granulomatous dermatitis and lymphadenitis. Pesquisa Veterinária Brasileira 33(1):1-4. Instituto Nacional de Tecnología Agropecuaria (INTA), Estación Experimental Agropecuaria Balcarce, Ruta 226 Km 73,5 (7620) Balcarce, Argentina. E-m...

Mycosis fungoides (MF), a low-grade lymphoproliferative disorder, is the most common type of cutaneous T-cell lymphoma. Typically, neoplastic T cells localize to the skin and produce patches, plaques, tumours or erythroderma. Diagnosis of MF can be difficult due to highly variable presentations and the sometimes nonspecific nature of histological findings. Molecular biology has improved the dia...

A 33-year-old male was referred to our department with a three-month history of weakness, nonproductive cough and asymptomatic skin lesions of both legs. His medical history included asthma that was medicated with montelukast, budesonide and formoterol. A physical examination showed confluent erythematous annular plaques, circumferentially distributed on both legs and associated with edema (Fig...

Parvovirus B19 infections in adults are usually associated with nonspecific and mild symptoms. However, cases presenting with a lupus-like syndrome have been described, leading to the hypothesis that parvovirus infection can induce connective tissue disease. Various histopathologic features of cutaneous manifestations of parvovirus have been reported, including features which overlap with those...