BACKGROUND The primary objective of this study was to investigate if extended antibiotic treatment against bacterial vaginosis (BV) together with adjuvant lactobacilli treatment could cure BV and, furthermore, to investigate factors that could cause relapse. METHODS In all, 63 consecutive women with bacterial vaginosis diagnosed by Amsel criteria were offered a much more aggressive treatment ...

OBJECTIVE To evaluate the comparative efficacy of 400 mg albendazole (Smith Kline Beecham) as a single dose and three brands of mebendazole (Janssen, Unibios and East African Pharmaceuticals) at doses of 100 mg twice a day for three consecutive days in the treatment of single or mixed infections with Ascaris lumbricoides and or Trichuris trichiura in four treatment groups of school children. ...

Susceptibility of Neisseria gonorrhoeae to gentamicin, the primary treatment for gonorrhea in Malawi since 1993, was determined by using agar dilution MICs, E-test MICs, disc diffusion, and clinical cure rate. Agar dilution MICs were slightly higher in 1996 than in 1993 isolates, with a concomitant drop in the clinical cure rate. E-test MICs were substantially lower than agar dilution determina...

BACKGROUND AND PURPOSE Endovascular therapy with liquid embolic agents is a common treatment strategy for cranial dural arteriovenous fistulas. This study evaluated the long-term effectiveness of transarterial Onyx as the single embolic agent for curative embolization of noncavernous cranial dural arteriovenous fistulas. MATERIALS AND METHODS We performed a retrospective review of 40 consecut...

nanocomposite samples based on elastomer blends of butyl rubber (iir) and ethylene propylene diene monomer (epdm) were prepared using a laboratory scale two-roll mill in order to study the effect of cloisite 15a organoclay content (i.e., 1, 3, 5 and 7 wt%) on the mechanical and morphological properties  of  iir/epdm/cloisite  15a  nanocomposites  compared  to  the  unflled epdm/iir blends. rheo...

We give a rigorous analysis of variations of the contact process on a finite graph in which the cure rate is allowed to vary from one vertex to the next, and even to depend on the current state of the system. In particular, we study the epidemic threshold in the models where the cure rate is proportional to the degree of the node or when it is proportional to the number of its infected neighbors.

BACKGROUND & OBJECTIVES Early diagnosis of tuberculosis (TB) is important for initiating treatment to gain cure. The present investigation was undertaken to study the association of conversion and cure with initial smear grading among pulmonary tuberculosis (TB) patients registered in a directly observed treatment - short course (DOTS) programme in Tiruvallur district, south India. METHODS Al...

BACKGROUND Treatment guidelines recommend stopping all implicated antibiotics at the onset of Clostridium difficile infection (CDI), but many individuals have persistent or new infections necessitating the use of concomitant antibiotics (CAs). We used data from 2 phase 3 trials to study effects of CAs on response to fidaxomicin or vancomycin. METHODS Subjects with CDI were treated for 10 days...

BACKGROUND There is significant variation in Amphotericin B (AMB) efficacy and relapses in antimony unresponsive visceral leishmaniasis (VL) cases over a period of time (10-15 years). Keeping in mind the above mentioned view this study was undertaken with an objective to assess the magnitude of cure and relapse rates of AMB in the treatment of antimony unresponsive VL cases. METHODS In a cont...

Oligohydramnios is an ominous pregnant complication with high perinatal morbidity and mortality of 80%-90%, if it was observed in second trimester. However, there is no promising modality to cure it at that period. In this case, heparin therapy was successful in an early onset extreme oligohydramnios.