Objective: In this study, we aimed to validate the accuracy of computed tomography-based attenuation correction (CTAC) using the bilinear scaling method.Methods: The measured attenuation coefficient (μm) was compared to a theoretical attenuation coefficient (μt ) using four different CT scanners and an RMI 467 phantom. The effective energy of the CT beam X-rays was calculated, using the aluminu...

The regional travel demand models are generally macroscopic in nature and do not include traffic controls in the traffic assignment process. In travel demand models, the road capacities are kept fixed within the functional classification of roadways and free-flow-speeds are adjusted to accommodate the impacts of traffic controls and traffic operations. Part of the reason this approach is adopte...

RE D IT S: (L EF T) P A U L BA TI ST A /M A SS G EN ER A L; (R IG H T) H .B RE IT ER /M A SS G EN ER A L BOSTON—Thanks to drug-war money, Massachusetts General Hospital just dedicated one of the most sophisticated magnetic resonance imaging machines around. With a whole-body magnet and a 460-ton steel shield, the multimillion-dollar device promises to give researchers new insight into the brain...

A series of 10-methyl-9-(phenoxycarbonyl)acridinium trifluoromethanesulfonates (XAEs), bearing substituents of various characteristics in the lateral benzene ring (2-halogen, 2,6-dihalogen, 2-trifluoromethyl, 2-nitro, 2-methoxy, 3-halogen and 4-halogen) were synthesized with high yields, identified and subjected to a physicochemical and theoretical investigation. The main task of the work was t...

Biomedical imaging is a rapidly growing field to provide a state-of-the-art tool for preclinical biomedical research and clinical applications, in view of its ability to noninvasively reveal subtle structural variations of biological tissues and visualize in vivo physiological and pathological processes at the cellular and molecular levels. Mathematical methods are involved with imaging theorie...

Fluorescence techniques have been widely used for the determination of micellar aggregation numbers.' However, the interpretation of the fluorescence data and the consequent estimates for the micellar aggregation numbers are not always unambiguous. The results usually depend on both the type of experiments performed and the micellar models invoked for the data analysis. In an interesting recent...

PURPOSE Dual-energy CT (DECT) is arguably the most accurate energy mapping technique in CT-based attenuation correction (CTAC) implemented on hybrid PET/CT systems. However, this approach is not attractive for clinical use owing to increased patient dose. The authors propose a novel energy mapping approach referred to as virtual DECT (VDECT) taking advantage of the DECT formulation but using CT...

•Synthesis of mesoporous, amorphous calcium-phosphate citrate nanoparticles•Induction apoptosis selectively in cancer cells•Excellent growth inhibition pleural tumors with minimal adverse effects Pleural are often highly aggressive and rapidly growing. Their proximity to the lung requires selective anticancer agents avoid effects. Such a agent is an urgent, yet unmet clinical need. A promising ...

Intestinal metaplasia of the oesophagus (Barrett’s oesophagus) is the most important risk factor for oesophageal adenocarcinoma. Although the role of mixed bile and acid gastro-oesophageal reflux is well established, the contribution of nuclear receptor signalling in the pathogenesis of Barrett’s oesophagus remains largely unknown. The recent article by Chang et al. (Gut 2007;56:906–17) showing...