Background: A new diagnosis of Crohn disease during pregnancy is uncommon. Intra-abdominal abscess as an initial feature of Crohn disease during pregnancy is rare. Case: A 26-year-old healthy primigravida woman at 33 weeks of gestation presented with abdominal pain and an abdominal mass. Labor was induced at 37 weeks to expedite postpartum evaluation. On postpartum day 2 she developed septic sh...

Colorectal cancer is the third most common in both men and women. Environmental genetic factors play a role development of colorectal carcinomaThe majority cancers are sporadic, with hereditary syndrome accounting for 10% cases. Precursor lesions like adenoma that transform into adenocarcinoma cause cancers. : A total 72 malignancies were studied histopathological features. The histologic featu...

We report here a case of drug-induced acute pancreatitis proved by elimination and single, low dose challenge test in a child with Crohn disease. A 14-year-old boy with moderate/severe Crohn disease was admitted due to high fever and severe epigastric pain during administration of mesalazine and azathioprine. Blood test and abdominal ultrasonography revealed acute pancreatitis. After discontinu...

Introduction Inflammatory bowel disease (IBD) consists of ulcerative colitis (UC), Crohn disease (CD), and indeterminate colitis. While sharing many clinical features, ulcerative colitis and Crohn disease are considered separate entities with unique characteristics. Due to the chronic nature of these diseases, frequent and repeated imaging is often necessary for diagnosis and therapeutic planni...

Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease of the gastrointestinal tract. There is a well-known risk of thrombosis in patients with IBD with an overall incidence of 1.3-7.5%. Cerebral venous sinus thrombosis (CVST) has been reported as an uncommon complication of IBD. It is suspected to be a consequence of genetic predisposition and the hypercoagulable state occurrin...

Pancreatic autoantibodies are Crohn disease-specific serologic markers. The function and immunological role of their recently identified autoantigen, glycoprotein 2 (GP2), are unknown. We therefore investigated the impact of GP2 on modulation of innate and adaptive immune responses to evaluate its potential therapeutic use in mucosal inflammation. Our data indicate a previously unknown function...

The clinical safety of measles and measles-mumps-rubella vaccines has been questioned in recent reports that propose a possible link between measles virus or measles vaccines and the occurrence of juvenile Crohn disease and autism. This article reviews the outcomes of several laboratory investigations which were carried out independently to identify the presence or absence of measles virus in t...

Natural History of Pediatric Crohn Disease T he natural history of pediatric Crohn disease (CD) remains unpredictable, although some trends are observed that differentiate children from adults. Pediatric CD often presents with more severe disease and more frequent need for immunosuppressive therapy (1). Growth failure, present in 15% to 20% of patients, is a unique characteristic of pediatric C...

AMAÇ: Crohn hastalığının (CH) tedavisinde birçok yeni gelişme olmasına karşın cerrahi tedavi gereksinimi hastalığın çeşitli dönemlerinde %70-90 arasındadır. Cerrahi endikasyonları komplikasyonlar ve medikal yetersizliği olmak üzere iki ana başlıkta toplanabilir. Bu çalışma; kliniğimizde CH nedeni ile acil şartlarda opere edilen hastalarımızın tedavilerini, sonuçlarını belirtmek preop tanısı ola...