Objectives—During an epidemiological study of Creutzfeldt-Jakob disease in Germany, Hashimoto’s encephalitis was encountered as a diVerential diagnosis, which has not yet been described in this

BACKGROUND Approximately 2% of Alzheimer disease cases and 10% to 15% of prion disease cases are due to mutations in autosomal dominant genes. Mutations have been found in patients without family histories of neurological disease. OBJECTIVES To emphasize the need for consideration of a genetic etiology of prion disease and early-onset Alzheimer disease, regardless of the absence of a signific...

Creutzfeldt-Jakob disease is a 'slow virus' illness usually presenting as a rapidly progressive dementia. Although rare, its laboratory and accidental transmission has given it great theoretical importance. However, the infective agent remains mysterious and it is not known how, or even whether, natural transmission occurs. Clinical diagnosis is difficult, treatment unfortunately unsuccessful a...

43. Jayanthi P, Thomas P, Bindhu P, Krishnapillai R. Prion diseases in humans: oral and dental implications. N Am J Med Sci. 2013;5:399–403. http://dx.doi.org/10.4103/1947-2714.115766 44. Peden A, McCardle L, Head MW, Love S, Ward HJ, Cousens SN, et al. Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia. Haemophilia. 2010; 16:296–304. http://d...

The following is an overview of the emerging issue of handling the dead human body with Creutzfeldt-Jakob Disease. The purpose is to educate the reader to what the disease is and is not and to better prepare the funeral service professional cremationist to service clientele while protecting the public end employees of the crematory. Creutzfeldt-Jakob Disease (CJD) is a relatively new disease ha...